Name | Quinapril |
Synonyms | Asig CI-906 ACCUPRO ACCUPRIL Accupril ACCUPRIN Quinapril PD-109452-2 QUINAPRIL HCL (S)-2-((S)-2-(((S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl)aMino)propanoyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid (3S)-2-[(2S)-2-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1,2,3,4-tetrahydro-3-Isoquinolinecarboxylic acid |
CAS | 85441-61-8 |
EINECS | 1312995-182-4 |
InChI | InChI=1/C25H30N2O5/c1-3-32-25(31)21(14-13-18-9-5-4-6-10-18)26-17(2)23(28)27-16-20-12-8-7-11-19(20)15-22(27)24(29)30/h4-12,17,21-22,26H,3,13-16H2,1-2H3,(H,29,30)/t17-,21-,22-/m0/s1 |
Molecular Formula | C25H30N2O5 |
Molar Mass | 438.52 |
Density | 1.217±0.06 g/cm3(Predicted) |
Melting Point | 120-130°C |
Boling Point | 662.0±55.0 °C(Predicted) |
pKa | 3.39±0.20(Predicted) |
Physical and Chemical Properties | Quinapril Hydrochloride: C25H30N2O5? HCl. [82586-55-8]. Crystallized from ethyl acetate-toluene, M. P. 14.5-130 °c,[α] d 25 1.2 °(C =, ethanol). Or a white crystalline solid was obtained from acetonitrile, melting point 119-121.5 ° C., [α]D25 15.4 °(C = 2, methanol). Acute toxicity LD50 male and female mice, male and female rats (mg/kg):1739,1840. 4280.3541 oral; 504,523,158,107 intravenous. Quinaprilat: C23H26N2O5. [82768-85-2]. Diacid of quinapril. Its hydrate crystals were obtained from methanol-ether, melting point 166-168 °c. [Α] D23 20.9 °(C = 1, methanol). |
Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. |