Acetamide,2-chloro-N-methyl-N-(4-nitrophenyl)-
2-CHLORO-N-METHYL-N-(4-NITROPHENYL)ACETAMIDE
CAS: 2653-16-9
Molecular Formula: C9H9ClN2O3
Acetamide,2-chloro-N-methyl-N-(4-nitrophenyl)- - Names and Identifiers
| Name | 2-CHLORO-N-METHYL-N-(4-NITROPHENYL)ACETAMIDE |
| Synonyms | Nintedanib-004 IntedanibImpurity11 Nintedanibintermediate 2-Chloro-N-methyl-4'-nitroacetanilide 2-CHLORO-N-METHYL-N-(4-NITROPHENYL)ACETAMIDE Acetamide,2-chloro-N-methyl-N-(4-nitrophenyl)- |
| CAS | 2653-16-9 |
Acetamide,2-chloro-N-methyl-N-(4-nitrophenyl)- - Physico-chemical Properties
| Molecular Formula | C9H9ClN2O3 |
| Molar Mass | 228.63236 |
| Density | 1.391±0.06 g/cm3(Predicted) |
| Melting Point | 109.5-110 °C |
| Boling Point | 374.9±27.0 °C(Predicted) |
| Storage Condition | 2-8℃ |
Acetamide,2-chloro-N-methyl-N-(4-nitrophenyl)- - Introduction
2-CHLORO-N-METHYL-N-(4-NITROPHENYL)ACETAMIDE is an organic compound. The following is a detailed description of the properties, uses, preparation and safety information of the compound:
Nature:
-Molecular formula: C9H9ClN2O3
-Molecular weight: 224.63g/mol
-Appearance: The compound was a white crystalline solid.
-Melting point: about 170-172°C
-Solubility: This compound is soluble in some organic solvents, such as dimethyl sulfoxide, dimethyl formamide, etc.
Use:
- 2-CHLORO-N-METHYL-N-(4-NITROPHENYL)ACETAMIDE is commonly used as an intermediate or reagent in organic synthesis and is used in the synthesis of other organic compounds.
-For example, it can be used to synthesize biologically active compounds, such as drugs or pesticides.
-In addition, the nitro substituent of the compound may make it active in some electrochemical applications.
Preparation Method:
2-CHLORO-N-METHYL-N-(4-NITROPHENYL)ACETAMIDE can be prepared by the following steps:
1. First, 4-nitrobenzoyl chloride is reacted with methylamine in the presence of a base to obtain 4-nitrobenzamide.
2. Next, the obtained 4-nitrobenzamide is reacted with chloroacetic anhydride in an alkaline medium to obtain 2-CHLORO-N-METHYL-N-(4-NITROPHENYL)ACETAMIDE.
Safety Information:
-This compound is an organochlorine compound and has certain toxicity.
-During operation, take appropriate protective measures, such as wearing protective glasses, gloves and laboratory clothing, to avoid skin contact, inhalation or ingestion.
-Avoid reacting with oxidants, strong acids or bases to avoid dangerous situations.
-Do not discharge the compound into the environment, and should be properly handled and disposed of in accordance with local regulations.
Please note that the synthesis and use of such chemicals should be carried out under the guidance of personnel trained in chemistry and must comply with laboratory safety regulations.
Nature:
-Molecular formula: C9H9ClN2O3
-Molecular weight: 224.63g/mol
-Appearance: The compound was a white crystalline solid.
-Melting point: about 170-172°C
-Solubility: This compound is soluble in some organic solvents, such as dimethyl sulfoxide, dimethyl formamide, etc.
Use:
- 2-CHLORO-N-METHYL-N-(4-NITROPHENYL)ACETAMIDE is commonly used as an intermediate or reagent in organic synthesis and is used in the synthesis of other organic compounds.
-For example, it can be used to synthesize biologically active compounds, such as drugs or pesticides.
-In addition, the nitro substituent of the compound may make it active in some electrochemical applications.
Preparation Method:
2-CHLORO-N-METHYL-N-(4-NITROPHENYL)ACETAMIDE can be prepared by the following steps:
1. First, 4-nitrobenzoyl chloride is reacted with methylamine in the presence of a base to obtain 4-nitrobenzamide.
2. Next, the obtained 4-nitrobenzamide is reacted with chloroacetic anhydride in an alkaline medium to obtain 2-CHLORO-N-METHYL-N-(4-NITROPHENYL)ACETAMIDE.
Safety Information:
-This compound is an organochlorine compound and has certain toxicity.
-During operation, take appropriate protective measures, such as wearing protective glasses, gloves and laboratory clothing, to avoid skin contact, inhalation or ingestion.
-Avoid reacting with oxidants, strong acids or bases to avoid dangerous situations.
-Do not discharge the compound into the environment, and should be properly handled and disposed of in accordance with local regulations.
Please note that the synthesis and use of such chemicals should be carried out under the guidance of personnel trained in chemistry and must comply with laboratory safety regulations.
Last Update：2024-04-09 21:01:54
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Product Name: Nintedanib Impurity 27 Visit Supplier Webpage Request for quotationCAS: 2653-16-9
Tel: 0714-3999186
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Multiple Specifications
Product Name: 2-CHLORO-N-METHYL-N-(4-NITROPHENYL)ACETAMIDE Visit Supplier Webpage Request for quotationCAS: 2653-16-9
Tel: 18301782025
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Product Name: 2-CHLORO-N-METHYL-N-(4-NITROPHENYL)ACETAMIDE Request for quotation
CAS: 2653-16-9
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CAS: 2653-16-9
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Email: sales02@cooperate-pharm.com
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