Acetoacetamide
Acetoacetamide
CAS: 5977-14-0
Molecular Formula: C4H7NO2
Acetoacetamide - Names and Identifiers
| Name | Acetoacetamide |
| Synonyms | Aids134414 Acetoacetamide ACETIACETAMIDE 3-Oxobutanamid 3-Oxobutanamide 3-Oxobutyramide β-Oxobutanamide Acetyl acetomide acetessigsaureamid butanamide, 3-oxo- ACETOACETAMIDE PURUM alpha-acetylacetamide |
| CAS | 5977-14-0 |
| EINECS | 227-774-4 |
| InChI | InChI=1/C4H7NO2/c1-3(6)2-4(5)7/h2H2,1H3,(H2,5,7) |
| InChIKey | GCPWJFKTWGFEHH-UHFFFAOYSA-N |
Acetoacetamide - Physico-chemical Properties
| Molecular Formula | C4H7NO2 |
| Molar Mass | 101.1 |
| Density | 1.093±0.06 g/cm3(Predicted) |
| Melting Point | 53-56°C(lit.) |
| Boling Point | 271.0±23.0 °C(Predicted) |
| Flash Point | >230°F |
| Water Solubility | 1000g/L at 20℃ |
| Solubility | water: soluble1g/10 mL, clear, colorless |
| Vapor Presure | 0.93Pa at 20℃ |
| Appearance | Crystalline Powder |
| Color | white to yellowish |
| BRN | 1560550 |
| pKa | 12.38±0.46(Predicted) |
| Storage Condition | Refrigerator |
| Refractive Index | 1.435 |
| Physical and Chemical Properties | The pure product is colorless needle-like crystal, has the pungent odor, the tear is extremely strong. The melting point of 79 deg C, boiling point of 223.5 deg C. Soluble in water, ethanol and ether, slightly soluble in other solvents. Unstable, long-term storage and easy to deteriorate, iron discoloration, so that the content decreased. |
| Use | Used as a raw material for analgin and antipyrine |
Acetoacetamide - Risk and Safety
| WGK Germany | 1 |
| RTECS | EJ3667188 |
Acetoacetamide - Nature
Open Data Verified Data
The Pure product is colorless needle-like crystal, has a pungent odor, and is unstable. Melting Point 79. Boiling point 223.5 °c. Soluble in water, ethanol and ether, slightly soluble in other solvents. Long-term storage is easy to deteriorate, when iron discoloration, so that the content decreased.
Last Update：2024-01-02 23:10:35
Acetoacetamide - Preparation Method
Open Data Verified Data
glacial acetic acid is cleaved to produce ketene, then polymerized to produce diketene, and then ammoniated with ammonia to obtain the product.
Last Update：2022-01-01 10:36:00
Acetoacetamide - Use
Open Data Verified Data
mainly used as pharmaceutical and dye intermediates, can be prepared pyrazolone, benzyl pyrazolone, etc.
Last Update：2022-01-01 10:36:00
Acetoacetamide - Safety
Open Data Verified Data
- This product is toxic, damage to the liver and kidney, long-term contact can cause neurasthenia, abnormal liver function and other symptoms. Production equipment should be closed, strengthen ventilation, the operator should wear protective equipment, try to avoid contact with the skin.
- packaged in iron or stainless steel tanks. The product is alkaline substances, unstable, not long storage. General products are sold in 20% to 24% aqueous solutions. According to the provisions of the storage and transportation of toxic chemicals.
Last Update：2022-01-01 10:36:01
Acetoacetamide - Reference Information
| LogP | -1.4 at 23℃ |
| EPA chemical substance information | information provided by: ofmpeb.epa.gov (external link) |
| Use | as butanone acylating agent, synthesis of butanone derivatives, widely used in medicine, dye intermediates, preparation of pyrazolone, benzylpyrazolone and the like are raw materials of metamizole sodium and antipyrine. used as raw material of analgin and antipyrine |
| production method | acetoacetamide is obtained by cleaving glacial acetic acid to ketene, polymerizing ketene to form diketene, and then ammoniating with ammonia. Raw material consumption quota: glacial acetic acid (95%)1638kg/t, ammonia (20%)950kg/t. |
Last Update：2024-04-09 21:11:58
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Tel: +86-17551318830
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Product Name: Acetoacetamide Visit Supplier Webpage Request for quotationCAS: 5977-14-0
Tel: 18301782025
Email: 3008007409@qq.com
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