Name | O~11~-acetyl-13-methylchelidonine |
Synonyms | Acetylcorynoline acetyl corynoline Corynoline acetate O-Acetylcorynoline ACETYLCORYNOLINE(P) (+)-Corynoline Acetate O~11~-acetyl-13-methylchelidonine (5bR,6S,12bR)-5b,6,7,12b,13,14-Hexahydro-5b,13-dimethyl-[1,3]benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridin-6-ol 6-acetate [1,3]Benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridin-6-ol,5b,6,7,12b,13,14-hexahydro-5b,13-dimethyl-, 6-acetate, (5bR,6S,12bR)- |
CAS | 18797-80-3 |
InChI | InChI=1/C23H23NO6/c1-12(25)30-20-7-13-6-18-19(28-10-27-18)8-14(13)22-23(20,2)16-4-5-17-21(29-11-26-17)15(16)9-24(22)3/h4-6,8,20,22H,7,9-11H2,1-3H3/t20-,22+,23-/m0/s1 |
Molecular Formula | C23H23NO6 |
Molar Mass | 409.43 |
Density | 1.42 |
Melting Point | 158~159℃ |
Boling Point | 499.1°C at 760 mmHg |
Flash Point | 255.7°C |
Solubility | Soluble in methanol, ethanol, DMSO and other organic solvents |
Vapor Presure | 4.26E-10mmHg at 25°C |
Appearance | Colorless crystal |
Storage Condition | 2-8℃ |
Refractive Index | 1.667 |
MDL | MFCD28385837 |
Physical and Chemical Properties | Yellow powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from Yunqianhu Peucedanum rubricaule, purple fish rushes Corydalis incisa. Kudiche, Corydalis with root, whole grass Kudiche. |
HS Code | 29399990 |
product description | bitter di ding is the root-carrying whole grass of corydalis, a poppy plant. traditional Chinese medicine is used to clear away heat and detoxify, promote blood circulation and reduce swelling, treat colds, cough, hepatitis and various inflammations, especially for rheumatism and myocarditis. Acetyl Corydalis is the main component of Kuditin. It is reported to have sedative, anti-leptospira and protective effects on liver injury, especially the latter. |
biological activity | Acetylcorynoline is the main alkaloid component derived from Chinese herbal Corydalis bungeana and has anti-inflammatory properties. Acetylcorynoline may inhibit the apoptosis pathway by reducing the expression of egl-1 and increase the expression of rpn5 to enhance the activity of proteasomes. |
target | TargetValue egl-1 () rpn5 () Proteasome () |
Target | Value |
chemical properties | yellow powder, soluble in organic solvents such as methanol, ethanol, DMSO, etc., derived from peucedanum Peucedanum rubricaule, purple fish lantern Corydalis incisa. Kudiche, Corydalis with root, whole grass Kudiche. |
use | acetyl violet has sedative and liver-protecting effects. used for content determination/identification/pharmacological experiments and other pharmacological effects: with sedative, anti-leptospira and liver injury protection. |