Adefovir-d4 - Names and Identifiers
Adefovir-d4 - Physico-chemical Properties
Molecular Formula | C8H12N5O4P
|
Molar Mass | 273.185741 |
Melting Point | >300°C (dec.) |
Storage Condition | -20°C Freezer, Under Inert Atmosphere |
Adefovir-d4 - Introduction
Adefovir-d4 is a deoxybalatinib analog with the chemical name (2R)-[4-(6-amino-9H-purin-9-yl)butyl]-(2S)-hydroxy-phosphonoacetate-d4. It is a stable isotope labeled desoxobalatinib with multiple deuterium (deuterium) substitutions used in drug metabolism studies and pharmacokinetic studies.
The main use of Adefovir-d4 is as a reference substance or internal standard in drug research, for the determination of the metabolic products of balatinib (Adefovir) and the enzymatic reaction of drug metabolizing enzymes. It can be used to study the pharmacokinetics, drug interactions and drug metabolic pathways of balatinib.
The preparation of Adefovir-d4 generally uses chemical synthesis methods, including cyclization reaction, substitution reaction and deoxygenation reaction steps. The detailed steps of the specific preparation method need to refer to the relevant synthesis literature or patent.
Safety information regarding Adefovir-d4, as a chemical agent, requires compliance with relevant safety practices. Wear appropriate personal protective equipment to avoid contact with eyes, skin and ingestion. Should be stored in a dry, low temperature, well-ventilated place, away from fire and flammable materials. In case of accidental contact or ingestion, seek medical attention immediately and bring the relevant chemical safety instructions. During use, please follow the relevant regulations and the unit's operating guidelines.
Last Update:2024-04-09 21:54:55