Aids000013
3'-Azido-2',3'-dideoxyadenosine
CAS: 66323-44-2
Molecular Formula: C10H12N8O2
Aids000013 - Names and Identifiers
| Name | 3'-Azido-2',3'-dideoxyadenosine |
| Synonyms | Aza 3'-Az-ddA 3'-N3-Dda Aids000013 3'-Azddado Aids-000013 3'-Azido-dda 3'-Azido-2',3'-dideoxyadenosine [(2S,3S,5R)-5-(6-Aminopurin-9-yl)-3-azidooxolan-2-yl]methanol 9-(3'-Azido-2',3'-dideoxy-.beta.-D-erythro-pentofuranosyl)adenine |
| CAS | 66323-44-2 |
| InChI | InChI=1/C10H12N8O2/c11-9-8-10(14-3-13-9)18(4-15-8)7-1-5(16-17-12)6(2-19)20-7/h3-7,19H,1-2H2,(H2,11,13,14)/t5-,6+,7+/m0/s1 |
Aids000013 - Physico-chemical Properties
| Molecular Formula | C10H12N8O2 |
| Molar Mass | 276.25 |
| Melting Point | 186-187 °C |
Aids000013 - Introduction
3 '-Azido-2',3 '-dideoxyadenosine is a chemical substance whose chemical structure is such that an azide group is attached to the 3' carbon position of the adenosine molecule, while deoxygenating at the 2 'and 3' carbon positions. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: Usually white solid
-Solubility: Soluble in water and organic solvents
-Melting point: about 150-153°C
Use:
-Chemical research: 3 '-Azido-2',3 '-dideoxyadenosine are commonly used as labeling agents for the synthesis of DNA or RNA molecules. They can be used as probes, labels and inhibitors in research.
-Antiviral drug research and development: 3 '-Azido-2',3 '-dideoxyadenosine has potential application in the research and development of anti-HIV drugs, but it is still in the laboratory research stage.
Preparation Method:
- 3 '-Azido-2',3 '-dideoxyadenosine has many synthesis methods. The common method is to introduce azide group into the 3' carbon position of adenosine molecule through chemical synthesis, and carry out deoxygenation reaction at the 2 'and 3' carbon positions.
Safety Information:
- 3 '-Azido-2',3 '-dideoxyadenosine is a chemical substance and needs to be handled with caution.
-When using or operating, follow the laboratory's safe operating procedures and wear appropriate protective equipment, such as gloves and goggles, to prevent contact or inhalation of the substance.
-It needs to be stored properly and avoid mixing with other chemicals or exposure to light or moisture to maintain its stability and purity.
Nature:
-Appearance: Usually white solid
-Solubility: Soluble in water and organic solvents
-Melting point: about 150-153°C
Use:
-Chemical research: 3 '-Azido-2',3 '-dideoxyadenosine are commonly used as labeling agents for the synthesis of DNA or RNA molecules. They can be used as probes, labels and inhibitors in research.
-Antiviral drug research and development: 3 '-Azido-2',3 '-dideoxyadenosine has potential application in the research and development of anti-HIV drugs, but it is still in the laboratory research stage.
Preparation Method:
- 3 '-Azido-2',3 '-dideoxyadenosine has many synthesis methods. The common method is to introduce azide group into the 3' carbon position of adenosine molecule through chemical synthesis, and carry out deoxygenation reaction at the 2 'and 3' carbon positions.
Safety Information:
- 3 '-Azido-2',3 '-dideoxyadenosine is a chemical substance and needs to be handled with caution.
-When using or operating, follow the laboratory's safe operating procedures and wear appropriate protective equipment, such as gloves and goggles, to prevent contact or inhalation of the substance.
-It needs to be stored properly and avoid mixing with other chemicals or exposure to light or moisture to maintain its stability and purity.
Last Update：2024-04-09 02:00:48
