Aids098106 - Names and Identifiers
Name | Gartanin
|
Synonyms | Gartanin gartanin Aids098106 Aids-098106 1,3,5,8-Tetrahydroxy-2,4-bis(3-methyl-2-butenyl)xanthone 1,3,5,8-Tetrahydroxy-2,4-bis(3-methyl-2-butenyl)-9H-xanthen-9-one 1,3,5,8-tetrahydroxy-2,4-bis(3-methyl-2-butenyl)-9h-xanthen-9-one 9H-Xanthen-9-one, 1,3,5,8-tetrahydroxy-2,4-bis(3-methyl-2-butenyl)- 1,3,5,8-Tetrahydroxy-2,4-bis(3-methylbut-2-en-1-yl)-9H-xanthen-9-one
|
CAS | 33390-42-0
|
Aids098106 - Physico-chemical Properties
Molecular Formula | C23H24O6
|
Molar Mass | 396.43 |
Density | 1.326±0.06 g/cm3(Predicted) |
Melting Point | 167℃ |
Boling Point | 644.4±55.0 °C(Predicted) |
Solubility | Soluble in DMSO |
Appearance | Yellow powder |
pKa | 7.17±0.20(Predicted) |
Storage Condition | 2-8℃ |
MDL | MFCD09264654 |
In vitro study | Gartanin is a potential agent against glutamate-induced oxidative injury partially through increasing Nrf-2-independed HO-1 and AMPK/SIRT1/PGC-1α signaling pathways . Gartanin induces cell cycle arrest and autophagy and suppresses migration involving PI3K/Akt/mTOR and MAPK signalling pathway in human glioma cells . |
Aids098106 - Introduction
Gartanin, commonly known as TOPT, is a bianthracene compound. The following is a description of some of its properties, uses, methods and safety information:
Nature:
-Appearance: TOPT is light yellow crystalline powder
-Melting point: About 285-287 degrees Celsius
-Solubility: TOPT dissolves in some organic solvents (such as chloroform, dimethylformamide and dichloromethane), but is almost insoluble in water.
Use:
- TOPT is an important organic electroluminescent (OLED) material, which can be used to prepare light-emitting diodes, flat panel displays and organic solar cells.
-It can also be used as a material for organic infrared photodiodes, light-emitting electrochemical cells, organic field effect transistors and fluorescent markers.
Preparation Method:
- TOPT is usually obtained by synthesis. There are many methods for the specific steps of synthesis, but the common method is to react the precursor compound of TOPT with oxygen for oxidation reaction.
-In the process of synthesizing TOPT, attention should be paid to the control of temperature and reaction conditions to ensure the obtainment of high-purity products.
Safety Information:
- TOPT has low toxicity and has no obvious harm to human body under normal circumstances.
-However, as a chemical, it is still necessary to pay attention to safety measures when exposed, such as avoiding direct inhalation of powder, avoiding contact with skin and eyes, etc.
-Wear appropriate protective equipment such as goggles, gloves, and laboratory goggles when using or handling topts.
Please note that the above information is for reference only. When using or handling TOPT, please follow the specific safety operation guidelines and relevant regulations.
Last Update:2024-04-09 19:05:02