Name | Mitoridine |
Synonyms | Mitoridine Ajmalan-17-one (19E)-19,20-Didehydro-12-hydroxyajmalan-17-one Ajmalan-17-one, 19,20-didehydro-12-hydroxy-, (19E)- |
CAS | 3911-19-1 |
Molecular Formula | C20H22N2O2 |
Molar Mass | 322.4 |
Density | 1.41±0.1 g/cm3 (20 ºC 760 Torr) |
Melting Point | 322℃ |
Boling Point | 522.1±50.0 °C(Predicted) |
Specific Rotation(α) | (c, 1.04 in Py)+175 |
Solubility | Very slightly soluble (0.17 g/L) (25 °C) |
Appearance | Yellow crystal |
pKa | 9.72±0.20(Predicted) |
Storage Condition | 2-8℃ |
Overview | Rauvolfia (RauvolfiavomitoriaAfzel) is a plant of the genus Rauvola of the Apocynaceae. There are 135 species of Rauvolfia in the world, mainly distributed in America, Africa, Oceania and Asia. There are 9 species and 4 varieties in southern China. Rauvolfia is native to Ghana, West Africa. It has been successfully introduced in China in recent years, mainly distributed in Guangxi and Yunnan. From the 1950s to the 1970s, scientists from various countries conducted a lot of research on the alkaloids in this genus and discovered a series of monoterpenoid indole alkaloids. Studies have shown that the alkaloids of this genus have the effects of lowering blood pressure, resisting arrhythmia, improving cerebral blood circulation, sedation, and antibacterial. A few years ago, Rauvolfia vomit introduced from Ghana was planted and popularized in Simao area, and now it has reached more than 2000 hectares. Rauvolfia emetic is one of the chemical components of Rauvolfia emetic. |