Molecular Formula | C20H26N2O2 |
Molar Mass | 326.44 |
Density | 1.1117 (rough estimate) |
Melting Point | 189°C |
Boling Point | 464.47°C (rough estimate) |
Specific Rotation(α) | D18 +131° (c = 0.4 in chloroform); D20 +144° (c = 0.8 in chloroform) |
Water Solubility | 489.7mg/L(30 ºC) |
Solubility | Chloroform (Slightly), DMSO (Slightly) |
Appearance | Powder |
Color | White |
Merck | 13,194 |
pKa | pKa 8.2 (Uncertain) |
Storage Condition | 2-8°C |
Refractive Index | 1.6800 (estimate) |
In vitro study | Electrophysiological experiments are performed with human embryonic kidney (HEK) cells (whole-cell patch clamp) and Xenopus oocytes (double-electrode voltage clamp) expressing wild-type and mutant HERG channels. Ajmaline blocks HERG currents with an IC 50 of 1.0μM in HEK cells and 42.3μM in Xenopus oocytes. |
Hazard Symbols | Xn - Harmful |
Risk Codes | R25 - Toxic if swallowed R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. |
Safety Description | S13 - Keep away from food, drink and animal foodstuffs. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S36 - Wear suitable protective clothing. |
UN IDs | 1544 |
RTECS | AX8050000 |
Hazard Class | 6.1(b) |
Packing Group | III |
Toxicity | LD50 oral in rat: 360mg/kg |