Molecular Formula | C15H24O9 |
Molar Mass | 348.35 |
Density | 1.57 |
Boling Point | 617.9±55.0 °C(Predicted) |
Specific Rotation(α) | -172.1 (c, 0.53 in MeOH) |
Solubility | DMSO : ≥ 3.7 mg/mL (10.62 mM) |
Appearance | Pale yellow powder |
pKa | 12.80±0.70(Predicted) |
Storage Condition | 2-8 ℃, stored with nitrogen |
Sensitive | Easily absorbing moisture |
Physical and Chemical Properties | Light yellow powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from Rehmannia glutinosa. |
Reference Show more | 1. Wang Huisen, Liu Ming, Liang Ruifeng, et al. Optimization of extraction process of radix rehmanniae glycosides based on HPLC-PDA and nourishing Yin [J]. Shi Zhen, National Medicine, 2019, v.30;No.289(09):11-14. 2. Xie Caixia, Li Yajing, Zhang Miao, etc. Establishment of rapid analysis method for content of rehmannia glutinosa A, rehmannia glutinosa D and leonurus glycoside [J]. Chinese Journal of Experimental prescriptions, 2018, 024(006):47-54. 3. Zhang Zhenling, Wu Ruo-nan, Yu Wenna, et al. Study on integrated processing technology of raw rehmannia glutinosa in producing area [J]. Chinese herbal medicine, 2018, 49(20):56-61. 4. Yu Wenna, Zhang Zhenling, Li Keke, et al. Determination of iridoid glycosides in different parts of fresh rehmannia glutinosa flower [J]. Food Research and Development, 2017(14):143-146. 5. Song Linlin, Xue Shujuan, Wang Lili, Zhang Fei, Chen with Qing. Analysis of chemical constituents of radix rehmanniae with different storage years [J]. Chinese traditional medicines, 2020,42(10):2661-2669. 6. Min GU, Yi-Ping YUAN, Zi-Nan QIN, Yan XU, Nan-Nan SHI, Yan-Ping WANG, Hua-Qiang ZHAI, Zhong-Zhi QIAN, A combined quality evaluation method that integrates chemical constituents, appearance traits and origins of raw Rehmanniae Radix pieces, Chinese Journal 7. [IF=3.645] Zhuo Xu et al."Investigation of dynamic accumulation and regularity of nine glycosides and saccharides in Rehmannia glutinosa by rapid quantitative analysis technology."J Sep Sci. 2019 Apr;42(8):1489-1499 8. [IF=4.36] Chenglin Song et al."Deciphering the mechanism of Fang-Ji-Di-Huang-Decoction in ameliorating psoriasis-like skin inflammation via the inhibition of IL-23/Th17 cell axis."J Ethnopharmacol. 2021 Dec;281:114571 9. [IF=4.142] Wang Chenxi et al."Systematic quality evaluation of Peiyuan Tongnao capsule by offline two-dimensional liquid chromatography/quadrupole-Orbitrap mass spectrometry and adjusted parallel reaction monitoring of quality markers."Anal Bioanal Chem. 2019 Nov;4 10. [IF=3.935] Yong-Sheng Wu et al."Chemical profiling of Callicarpa nudiflora and its effective compounds identification by compound-target network analysis."J Pharmaceut Biomed. 2020 Apr;182:113110 11. [IF=3] Min GU et al."A combined quality evaluation method that integrates chemical constituents, appearance traits and origins of raw Rehmanniae Radix pieces."Chin J Nat Medicines. 2021 Jul;19:551 |
biological activity | Ajugol is an iridoether glycoside, which can be separated from Sideritis germanicopolitana. Ajugol has anti-protozoan activity with an IC50 of 31.8 μg/mL against the Trypanosoma B. rhodesiense Trypanosoma. |
chemical properties | light yellow powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from rehmannia glutinosa. |
use | used for content determination/identification/pharmacological experiments, etc. |