Name | Alectinib |
Synonyms | AF-802 Alectinib RO 5424802 |
CAS | 1256580-46-7 |
EINECS | 821-541-6 |
Molecular Formula | C30H34N4O2 |
Molar Mass | 482.62 |
Density | 1.28 |
Melting Point | 274-276°C |
Boling Point | 722.5±60.0 °C(Predicted) |
Appearance | Form solid, color White |
pKa | 13.70±0.40(Predicted) |
Storage Condition | -20° |
Stability | Stable for 1 year from date of purchase as supplied. Solutions are not stable and should be prepared fresh daily. |
Use | Alectinib (CH5424802) is a potent ALK inhibitor with an IC50 of 1.9 nM, sensitive to L1196M mutants, acting on ALK more selectively than PF-02341066, NVP-TAE684 and PHA-E429. |
1mg | 5mg | 10mg | |
---|---|---|---|
1 mM | 2.072 ml | 10.36 ml | 20.72 ml |
5 mM | 0.414 ml | 2.072 ml | 4.144 ml |
10 mM | 0.207 ml | 1.036 ml | 2.072 ml |
5 mM | 0.041 ml | 0.207 ml | 0.414 ml |