Name | 2-Aminopropanediamide |
Synonyms | NSC 75208 favipiravir-001 Aminomalonamide 2-Aminopropanediamide 2-aminopropanediamide 2-azanylpropanediamide Propanediamide, 2-amino- PropanediaMide, 2-aMino- 2-Aminopropane-1,3-diamide amino-malonic acid diamide |
CAS | 62009-47-6 |
EINECS | 263-370-4 |
InChI | InChI=1/C3H7N3O2/c4-1(2(5)7)3(6)8/h1H,4H2,(H2,5,7)(H2,6,8) |
Molecular Formula | C3H7N3O2 |
Molar Mass | 117.11 |
Density | 1.399±0.06 g/cm3(Predicted) |
Melting Point | 180-185°C |
Boling Point | 410.1±40.0 °C(Predicted) |
Flash Point | 201.8°C |
Solubility | DMSO (Sparingly), Methanol (Sparingly) |
Vapor Presure | 6.19E-07mmHg at 25°C |
Appearance | Solid |
Color | Pale Yellow to Beige |
pKa | 9.87±0.70(Predicted) |
Storage Condition | Keep in dark place,Inert atmosphere,2-8°C |
Refractive Index | 1.547 |
application | 2-aminomalondiamide is a pharmaceutical intermediate, which can be prepared from 2-aminomalonic acid ethyl ester in one step and can be used in laboratory research and development process and chemical production process. 2-aminomalonamide is an organic intermediate, which can be prepared from 2-aminomalonic acid ethyl ester in one step. It has been reported that 2-aminomalonamide can be used to prepare 2-aminomalononitrile and 2-methyl-5-carboxylic acid pyrazine. |
preparation | weigh 17.5g of 2-aminomalonic acid ethyl ester, 50% 22g of ammonium chloride aqueous solution, heat reflux at 100 degrees for 2 hours, filter after reaction, and dry with hot air at 60 degrees for 8 hours to obtain white 10.2 g2-aminomalonamide with a yield of 87%. |