Amprovine
amprolium
CAS: 121-25-5
Molecular Formula: C14H19N4.Cl
Amprovine - Names and Identifiers
Amprovine - Physico-chemical Properties
| Molecular Formula | C14H19N4.Cl |
| Molar Mass | 278.79 |
| Melting Point | 246-248 °C (decomp) |
| Color | Crystals from methanol + ethanol |
| Storage Condition | 0-6°C |
| Stability | Stable. Incompatible with strong acids, strong bases, strong oxidizing agents. |
Amprovine - Nature
Open Data Verified Data
aminopropioline hydrochloride white or off-white powder, odorless or almost odorless. Soluble in water, methanol or ethanol, slightly soluble in ether, insoluble in chloroform. The pH value of 10% aqueous solution is 2.5~3.0. Mixed into the feed, especially in the neutral conditions of slow decomposition, heating to 248~249 C decomposition.
Last Update：2024-01-02 23:10:35
Amprovine - Preparation Method
Open Data Verified Data
The intermediate for producing vitamin B1 is used as raw material, which is obtained by ring-opening by cyclization, hydrolysis, diazotization and condensation.
Last Update：2022-01-01 10:11:08
Amprovine - Use
Open Data Verified Data
The Anti-coccidiosis drug has better anti-coccidial effect. Aminopropioline has the strongest effect on chicken tender and pile-type Eimeria, but has a slightly poor effect on poison, Brinell, giant, and Eimeria retard, and is mostly used in combination with ethoxamide phenylmethyl Ester and sulfamethazine, to enhance the efficacy. It also had good preventive effect on Eimeria in calves and Eimeria in lambs.
Last Update：2022-01-01 10:11:09
Amprovine - Reference Information
| EPA chemical information | Information provided by: ofmpub.epa.gov (external link) |
| use | aminoproline hydrochloride is used as an intermediate in pharmaceutical raw materials. Aminopropoline hydrochloride is a traditional anti-coccidial drug and has been widely used in various countries in the world. The advantages of this medicine: ①It has a significant preventive effect on Ehrlich and poisonous Ehrlich, and has an inhibitory effect on giant Ehrlich and translocation Ehrlich. ②Among various anticoccal drugs, this variety has the highest safety anticoccal drugs |
| Application | Amprolin is used in chickens, rabbits, calves and lambs, and is effective for tender and pile-shaped Eimeria and lambs and calves. It is suitable for use with other drugs to make a water-soluble powder or premix. It is the main anti-coccidial drug for laying hens. The product has little toxicity, large safety range, less residue and no need to stop the drug. Most of them are made with ethoxyamidobenzene methyl ester and sulfaquinoxaline to expand the anti-coccidia spectrum and enhance the anti-coccidia effect. Combined with sulfaquinoxaline, it also has a good inhibitory effect on concurrent bacterial infection, and is an anti-coccidial drug widely used at present. |
| Biological activity | Amprolium is an anticoccidial drug used in poultry. It is a kind of thiamine, which inhibits thiamine absorption and carbohydrate synthesis. And inhibit the thiamine transport of coccidia. |
Last Update：2024-04-09 21:04:16
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