Name | Tamsulosin |
Synonyms | Amsulosin TAMSOLUSIN Tamsolusin TAMSULOSIN TANSULOSIN Tamsulosin TAMSULOSINE TamsulosinRHCl 5-[2-[2-(2-ethoxyphenoxy)ethylamino]propyl]-2-methoxy-benzenesulfonamide 5-[2-[2-(2-Ethoxyphenoxy)ethylamino]propyl]-2-methoxy-benzenesulfonamide 5-(2-{[2-(2-ethoxyphenoxy)ethyl]amino}propyl)-2-methoxybenzenesulfonamide 5-[(2R)-2-{[2-(2-ethoxyphenoxy)ethyl]amino}propyl]-2-methoxybenzenesulfonamide (R)(-)5-[2-[2-(2-Ethoxyphenoxy)ethyl]amino-propyl]-2-methoxybenzenesulfonmidehydrochloride |
CAS | 106133-20-4 |
EINECS | 600-716-9 |
InChI | InChI=1/C20H28N2O5S/c1-4-26-17-7-5-6-8-18(17)27-12-11-22-15(2)13-16-9-10-19(25-3)20(14-16)28(21,23)24/h5-10,14-15,22H,4,11-13H2,1-3H3,(H2,21,23,24)/t15-/m1/s1 |
Molecular Formula | C20H28N2O5S |
Molar Mass | 408.51 |
Density | 1.191±0.06 g/cm3(Predicted) |
Melting Point | 226-228°C |
Boling Point | 595.5±60.0 °C(Predicted) |
Flash Point | 313.9°C |
Vapor Presure | 3.79E-14mmHg at 25°C |
pKa | 10.08±0.60(Predicted) |
Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
Refractive Index | 1.553 |
1mg | 5mg | 10mg | |
---|---|---|---|
1 mM | 2.448 ml | 12.24 ml | 24.479 ml |
5 mM | 0.49 ml | 2.448 ml | 4.896 ml |
10 mM | 0.245 ml | 1.224 ml | 2.448 ml |
5 mM | 0.049 ml | 0.245 ml | 0.49 ml |
overview | tamsulosin hydrochloride (tamsulosinhydrochloride) is the third generation of superselective long-acting α1 inhibitor, which has a highly selective blocking effect on urethra, bladder neck and prostate smooth muscle, and is suitable for dysuria, frequent urination at night and residual urine caused by prostatic hyperplasia. |
Biological activity | Tamsulosin ((R)-(-)-YM12617 free base) is an α1-adrenergic receptor (α1-adrenergic receptor) inhibitor. Tamsulosin is often used in the study of prostatic hyperplasia. In animal models, Tamsulosin can slow down the growth of abdominal aortic aneurysm. |
use | urinary system medication. |
toxic substance data | information provided by: pubchem.ncbi.nlm.nih.gov (external link) |