Anwuligan
Anwuligan
CAS: 107534-93-0
Molecular Formula: C20H24O4
Anwuligan - Names and Identifiers
Anwuligan - Physico-chemical Properties
| Molecular Formula | C20H24O4 |
| Molar Mass | 328.4 |
| Density | 1.159 |
| Melting Point | 70-71℃ |
| Boling Point | 467.0±40.0 °C(Predicted) |
| Specific Rotation(α) | (c, 1.8 in CHCl3)+5.28 |
| Flash Point | 236℃ |
| Solubility | Soluble in chloroform, methanol |
| Appearance | White powder |
| pKa | 10.19±0.20(Predicted) |
| Storage Condition | 2-8℃ |
| MDL | MFCD09953803 |
| Physical and Chemical Properties | White crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, comes from the root or skin of Schisandra chinensis Schisandra chinensis. |
| In vitro study | Macelignan (1-50 μM; 72 hours) does not reduce cell viability alone, however, UVB treatment, even at the lowest dose of 30 mJ/cm 2 , reduces HaCaT cell viability in a dose-dependent mannner,it reduces approximately 80% of control values at 100 μM in hacat cells.Macelignan (0.1-1 μM; 24 hours) decreases COX-2 expression in a concentration-dependent manner,and at the highest concentration of macelignan (1 μM) , COX-2 expression is inhibited by almost 50% in hacat cells. Cell Viability Assay Cell Line: Hacat cells Concentration: 1 μM; 2.5 μM; 5 μM; 10 μM; 15 μM; 50 μM Incubation Time: 72 hours Result: Induced cell death by UVB irradiation at 30 mJ/cm 2 from 10 μM. Western Blot Analysis Cell Line: Hacat cells Concentration: 0.1 μM; 0.5 μM;1 μM Incubation Time: 24 hours Result: Reduced UVB-induced COX-2 expression in cells. |
| In vivo study | Macelignan (oral administration; 15 mg/kg; every day for three weeks) exhibits in vivo anti-diabetic effects. The baseline (day 0) fasting blood glucose levels does not differ between groups; at the end of the experiment, the values of the Macelignan-treated group are significantly lower compared to the diabetic control group in C57BL/KsJ- db/db mice. Animal Model: Male C57BL/KsJ- db/db mice Dosage: 15 mg/kg Administration: Oral administration; 15 mg/kg; every day for three weeks Result: Significantly reduced the blood glucose levels in mice. |
Anwuligan - Risk and Safety
| HS Code | 29329990 |
Anwuligan - Reference
| Reference Show more | 1. [IF=4.379] Wang Jinghui et al."A New Strategy for Deleting Animal drugs from Traditional Chinese Medicines based on Modified Yimusake Formula."Sci Rep-Uk. 2017 May;7(1):1-22 2. [IF=3.935] Yunlong Guo et al."Rapid characterization of Schisandra species by using direct analysis in real time mass spectrometry."J Pharmaceut Biomed. 2021 Jan;192:113648 |
Anwuligan - Introduction
Anwuligan, also known as N-pentenyl valerate, is an organic compound. The following is a brief introduction to some properties, uses, methods and safety information about Anwuligan:
Nature:
-Appearance: Anwuligan is a colorless to pale yellow liquid.
-Odor: with a special aroma.
-Density: 0.876g/cm³.
-Melting point:-87 ° C.
-Boiling point: 142 ° C.
-Solubility: Soluble in organic solvents, such as ethers, alcohols and ketones.
Use:
- Anwuligan is mainly used as a natural flavor, flavoring and food additive.
-It can be used as a flavor and spice for fruits, herbs and bakery products to enhance their taste and aroma.
- Anwuligan is also commonly used in the manufacture of perfumes, soaps, cosmetics and oral care products to provide a fragrant scent.
Preparation Method:
- Anwuligan can be prepared by esterification, that is, the reaction of pentanoic acid with N-pentenol to produce N-pentenoate.
Safety Information:
- Anwuligan is relatively safe for the human body under normal conditions of use, but it is still necessary to follow appropriate operating procedures, such as wearing appropriate personal protective equipment.
-Avoid contact with skin, eyes and respiratory tract.
-In case of ingestion or accidental inhalation, seek medical attention immediately.
-Should be stored in a closed container, away from fire and oxidizing agents.
-Good ventilation should be maintained when using or handling Anwuligan.
Please note that the above information is for reference only. When using or handling chemicals, strictly follow the appropriate safety procedures and refer to the specific safety information provided by the supplier.
Nature:
-Appearance: Anwuligan is a colorless to pale yellow liquid.
-Odor: with a special aroma.
-Density: 0.876g/cm³.
-Melting point:-87 ° C.
-Boiling point: 142 ° C.
-Solubility: Soluble in organic solvents, such as ethers, alcohols and ketones.
Use:
- Anwuligan is mainly used as a natural flavor, flavoring and food additive.
-It can be used as a flavor and spice for fruits, herbs and bakery products to enhance their taste and aroma.
- Anwuligan is also commonly used in the manufacture of perfumes, soaps, cosmetics and oral care products to provide a fragrant scent.
Preparation Method:
- Anwuligan can be prepared by esterification, that is, the reaction of pentanoic acid with N-pentenol to produce N-pentenoate.
Safety Information:
- Anwuligan is relatively safe for the human body under normal conditions of use, but it is still necessary to follow appropriate operating procedures, such as wearing appropriate personal protective equipment.
-Avoid contact with skin, eyes and respiratory tract.
-In case of ingestion or accidental inhalation, seek medical attention immediately.
-Should be stored in a closed container, away from fire and oxidizing agents.
-Good ventilation should be maintained when using or handling Anwuligan.
Please note that the above information is for reference only. When using or handling chemicals, strictly follow the appropriate safety procedures and refer to the specific safety information provided by the supplier.
Last Update：2024-04-09 15:16:35
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Product Name: Anwuligan Visit Supplier Webpage Request for quotationCAS: 107534-93-0
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Product Name: Anwuligan Visit Supplier Webpage Request for quotationCAS: 107534-93-0
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Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
Spot supply
Product Name: Anwuligan Visit Supplier Webpage Request for quotationCAS: 107534-93-0
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Spot supply
Product Name: Anwuligan Visit Supplier Webpage Request for quotationCAS: 107534-93-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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