Arglabine
arglabin
CAS: 84692-91-1
Molecular Formula: C15H18O3
Arglabine - Names and Identifiers
Arglabine - Physico-chemical Properties
| Molecular Formula | C15H18O3 |
| Molar Mass | 246.3 |
| Density | 1.22±0.1 g/cm3(Predicted) |
| Melting Point | 100-102 °C |
| Boling Point | 404.6±45.0 °C(Predicted) |
| Solubility | Slightly soluble (7.9g/L) (25°C), |
| Appearance | Powder |
| Color | Off-White |
| Storage Condition | Amber Vial, -20°C Freezer, Under inert atmosphere |
| In vitro study | The antitumor activity of arglabin proceeds through its inhibition of farnesyl transferase which leads to the activation of RAS proto-oncogene, a process that is believed to play a pivotal role in 20-30% of all human tumors. It actually inhibits the incorporation of farnesyl pyrophosphate into human H-ras proteins by the enzyme farnesyl transferase (FTase). |
| In vivo study | Arglabin reduces inflammation and plasma lipids, increases autophagy, and orients tissue macrophages into an anti-inflammatory phenotype in ApoE2.Ki mice fed a high-fat diet. |
Arglabine - Reference Information
| biological activity | Arglabin (( )-Arglabin), a natural product isolated from Artemisia annua L, it is a NLRP3 inflammatory body (NLRP3) inhibitor. Arglabin has anti-inflammatory and anti-tumor activity. The anti-tumor activity of Arglabin is achieved by activating the RAS proto-oncogene by inhibiting farnesyl transferase. |
Last Update：2024-04-09 20:49:11
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Spot supply
Product Name: Arglabin Visit Supplier Webpage Request for quotationCAS: 84692-91-1
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Spot supply
Product Name: arglabin Visit Supplier Webpage Request for quotationCAS: 84692-91-1
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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