Avroside
Isovitexin
CAS: 29702-25-8
Molecular Formula: C21H20O10
Avroside - Names and Identifiers
Avroside - Physico-chemical Properties
| Molecular Formula | C21H20O10 |
| Molar Mass | 432.38 |
| Melting Point | 220-221°C |
| Boling Point | 807ºC at 760mmHg |
| Specific Rotation(α) | -7.9°(Pyridine aqueous solution) |
| Solubility | Insoluble in cold water, slightly soluble in hot water and ethanol. |
| Appearance | Morphological Solid |
| Color | Light Yellow to Yellow |
| Storage Condition | Hygroscopic, Refrigerator, Under inert atmosphere |
| Stability | Hygroscopic |
| Physical and Chemical Properties | 化学性质 不溶于冷水，微溶于热水、乙醇。 小叶榕叶，来源于桑科榕属植物榕树（Ficus microcarpa L.f.）的叶。 |
| Use | Uses for content determination/identification/pharmacological experiments, etc. Pharmacological effects: Mainly used in the treatment of asthma and chronic bronchitis, in the treatment of cardiovascular disease, anti-inflammatory, antibacterial and other aspects also have significant effects. |
Avroside - Risk and Safety
| WGK Germany | 3 |
Avroside - Reference
| Reference Show more | 1. Liu Xiaozhou Wang Baoyu Chen Mingxi et al. Determination of related substances in isovitexin phospholipid complex by HPLC [J]. Journal of Shenyang Pharmaceutical University 2019(7):586-592. 2. Member Rongsun Lili Yang Liwei. Determination of vitexin and isovitexin in keteling capsules by one-Test double evaluation method [J]. Modern Chinese Medicine, 2015 v.17(06):82-86. 3. Von glorkham, safyaphone, Qiao Qian, et al. Study on apoptosis-inducing effect of isovitexin on rat hepatic stellate cells and its mechanism based on PI3K/Akt signaling pathway [J]. Journal of Guangxi Medical University, 2020, v.37(02):30-35. 4. Li Hongyan, Liang Jinhui, Liu Yingqiang. Quality standard of dry extract of Ficus microphylla [J]. Pharmacy Today, 2016, v.26(04):248-251. 5. Qiao Qian, Yafeng, Peng Xiaohong, et al. Protective effect of isovitexin on thioacetamide-induced acute liver injury in mice and its mechanism [J]. Journal of Guangxi Medical University, 2020, 037(003):388-392. 6. Li Qiuyan, Li Jingjing, Wang Bowen, etc. Analysis of aroma components of bamboo leaf extract and its application in cigarette [J]. Chemical World, 2019, 60(03):35-40. 7. Luo Lei, Ji Qinghua, Ma Liping, Fan Jinling, Zhu Wenxue, du Guanshang. Protective effect of mung bean Hull flavonoids on human umbilical vein endothelial cells injury induced by H_2O_2 [J]. Chinese Journal of Food Science, 2020,20(02):35-41. 8. Hu Qiqi, Zeng Rui, Yang Xiao, etc. Preliminary Study on the anti-tumor activity of extract quality markers of Humulus scandens [J]. Chinese herbal medicine, 2020(10):2642-2650. 9. Wang Zixuan, Li Yaqi, Xiao Zhijun, etc. Simultaneous determination of vitexin and isovitexin in Hugan Pian by HPLC [J]. Central South pharmacy, 2019, 29 (7):1092-1095. 10. Cao Dan, Jiang Yan, Lin Ruichao, et al. Determination of vitexin and isovitexin in Rhizoma dioscoreae by HPLC [J]. World Science and Technology-modernization of traditional Chinese medicine, 2015, 000(005):1012-1015. 11. Over Li-Nong, Zheng Yi-ya, Liu Jie, etc. Establishment of HPLC fingerprint of sinonovacula constricta and determination of two carbon glycosides [J]. China Pharmaceutical Affairs, 2017, 29 (09):1032-1038. 12. Wang Xiangbo, Jie Li Rui-Lian. Determination of four flavonoids in stems and leaves of Lysimachia officinalis by HPLC [J]. Chinese pharmacist 2019 v.22(07):170-172. 13. Zhang Yong, Feng Yuting, Ma Ninghui, etc. Comprehensive Evaluation of extraction technology of bamboo leaves [J]. Chinese Journal of Experimental prescriptions, 2018(17). 14. Guo Jing, Wang Haoran, Shen Zhouyuan, Zhang Tong, Yuan Xiurong, Ding Yue. Analysis of antioxidant components in three kinds of bamboo leaves [J]. Chinese patent medicine 2019 41(11):2688-2694. 15. Yang Wenning, Han Xing, Yang Haiyang, et al. Selection of quality control components of Gentiana macrophylla based on multi-component drug metabolism [J]. World Traditional Chinese Medicine, No. 13, vol. 15,, 1907, p. 2020. 16. Shi Jiawan, Zhang Ran, Liang Fuqiang, Cheng Yuxin, Zhang Tai. Screening and molecular mechanism of α-glucosidase inhibitors from cereal phytochemicals [J]. Food Science, 2021,42(05):9-16. 17. [IF = 5.279] Yong Sun et al."qualitative and Quantitative Analysis of Phenolics in tetrastigma hemsleyanum and Their antioxidant and antiproliferative Activities." J Agr Food Chem. 2013;61(44):10507-10515 18. [IF = 9.147] Jianzhong Zhu et al."Effect of Rosa Roxburghii juice on starch digestibility: A focus on the binding of polyphenols to amylose and porcine pancreatic α-amylase by molecular modeling."Food Hydrocolloid. 2022 Feb;123:106966 19. [IF=7.514] Chu-Yang Wang et al."Isolation of wheat mutants with higher grain phenolics to enhance anti-oxidant potential."Food Chem. 2020 Jan;303:125363 20. [IF=7.514] Xi Juan Zhao et al."A rapid UHPLC-QqQ-MS/MS method for the simultaneous qualitation and quantitation of coumarins, furocoumarins, flavonoids, phenolic acids in pummelo fruits."Food Chem. 2020 Sep;325:126835 21. [IF=5.81] Mu Jianfei et al."Determination of Polyphenols in Ilex kudingcha and Insect Tea (Leaves Altered by Animals) by Ultra-high-performance Liquid Chromatography-Triple Quadrupole Mass Spectrometry (UHPLC-QqQ-MS) and Comparison of Their Anti-Aging Effects."Fro 22. [IF=5.396] Mingfang Tao et al."Flavonoids from the mung bean coat promote longevity and fitness in Caenorhabditis elegans."Food Funct. 2021 Aug;12(17):8196-8207 23. [IF=4.411] Ning-Hui Ma et al."Antioxidant and Compositional HPLC Analysis of Three Common Bamboo Leaves."Molecules. 2020 Jan;25(2):409 24. [IF=4.162] Jiuling Deng et al."A Network Pharmacology-Based Investigation to the Pharmacodynamic Material Basis and Mechanisms of the Anti-Inflammatory and Anti-Viral Effect of Isatis indigotica."Drug Des Dev Ther. 2021; 15: 3193-3206 25. [IF=2.863] Xiaokang Liu et al."Spectrum-effect relationship between ultra-high-performance liquid chromatography fingerprints and antioxidant activities of Lophatherum gracile Brongn."Food Science & Nutrition. 2022 Feb 22 26. [IF=3.935] Junmao Li et al."Comprehensive chemical profiling of the flowers of Citrus aurantium L. var. amara Engl. and uncovering the active ingredients of lipid lowering."J Pharmaceut Biomed. 2022 Mar;211:114621 27. [IF=5.82] Mingfang Tao et al."Vitexin and Isovitexin Act Through Inhibition of Insulin Receptor to Promote Longevity and Fitness in Caenorhabditis elegans."MOLECULAR NUTRITION & FOOD RESEARCH. 2022 Apr 12 28. [IF=6.953] Yanqing Yang et al."The hypoglycemic and hypolipemic potentials of Moringa oleifera leaf polysaccharide and polysaccharide-flavonoid complex."INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES. 2022 May;: 29. [IF=7.514] Jie Meng et al."Conduction of a chemical structure-guided metabolic phenotype analysis method targeting phenylpropane pathway via LC-MS: Ginkgo biloba and soybean as examples."FOOD CHEMISTRY. 2022 Oct;390:133155 |
Avroside - Overview
Flavonoids (flavonoids) are secondary metabolites of plants, including a variety of oxyglycoflavones and carbon glycoflavones. Carbon glycoside flavone refers to the glycosyl group directly connected to the flavonoid matrix by C- C bond. It is reported in the literature that these compounds have a series of effects such as vasodilating, anticancer, antiplatelet and antiarrhythmic. From a structural point of view, iso-vitexin belongs to the active substance of carbon glycoside flavonoids, which is widely found in the roots, stems, leaves, bark, fruits and seeds of dozens of plants in nature. The existing relevant data show that IV has a variety of pharmacological activities, including hypoglycemic, antibacterial, memory regulation, α-glucosidase inhibition, blood pressure lowering and antioxidant effects. However, there is no special research on the role of the compound in other aspects.
Last Update：2024-04-10 22:29:15
Avroside - Reference Information
| overview | flavonoids (flavonoids) are secondary metabolites of plants, including a variety of oxyglycoflavones and carbon glycoflavones. Carbon glycoside flavone refers to the glycosyl group directly connected to the flavonoid matrix by C- C bond. It is reported in the literature that these compounds have a series of effects such as vasodilating, anticancer, antiplatelet and antiarrhythmic. From a structural point of view, iso-vitexin belongs to the active substance of carbon glycoside flavonoids, which is widely found in the roots, stems, leaves, bark, fruits and seeds of dozens of plants in nature. The existing relevant data show that IV has a variety of pharmacological activities, including hypoglycemic, antibacterial, memory regulation, α-glucosidase inhibition, blood pressure lowering and antioxidant effects. However, there is no special research on the role of the compound in other aspects. |
| chemical properties | insoluble in cold water, slightly soluble in hot water and ethanol. Ficus microphylla leaves, derived from the leaves of Ficus microcarpa L.f. |
| use | used for content determination/identification/pharmacological experiments, etc. Pharmacological effects: Mainly used in the treatment of asthma and chronic bronchitis, in the treatment of cardiovascular disease, anti-inflammatory, antibacterial and other aspects also have significant effects. |
Last Update：2024-04-09 20:52:54
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Featured ProductsSpot supply
Product Name: Isovitexin Visit Supplier Webpage Request for quotationCAS: 29702-25-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
Product Name: Isovitexin Request for quotation
CAS: 29702-25-8
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
CAS: 29702-25-8
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
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