Azide-PEG3-maleimide
Azido-PEG3-maleimide
CAS: 1858264-36-4
Molecular Formula: C15H23N5O6
Azide-PEG3-maleimide - Names and Identifiers
| Name | Azido-PEG3-maleimide |
| Synonyms | N3-PEG3-Mal Azide-PEG3-maleimide Azido-PEG3-Maleimide Azido-PEG3-maleimide |
| CAS | 1858264-36-4 |
Azide-PEG3-maleimide - Physico-chemical Properties
| Molecular Formula | C15H23N5O6 |
| Molar Mass | 369.37302 |
| Storage Condition | 2-8°C |
| In vitro study | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. |
Azide-PEG3-maleimide - Reference Information
| biological activity | Azido-PEG3-maleimide is a PROTAC linker, belonging to the PEG class, which can be used to synthesize PROTAC molecules. Azido-PEG3-maleimide is also a cleavable ADC linker containing 3 units of PEG, which can be used to synthesize antibody conjugated drugs (ADC). |
Last Update：2024-04-09 21:11:58
