Molecular Formula | C19H21Br2N3O |
Molar Mass | 467.2 |
Storage Condition | Keep in dark place,Inert atmosphere,Room temperature |
Reference Show more | 1. Zheng, Xiao-peng, et al. "Kidney-targeted baicalin-lysozyme conjugate ameliorates renal fibrosis in rats with diabetic nephropathy induced by streptozotocin." BMC nephrology 21 (2020): 1-17. |
1mg | 5mg | 10mg | |
---|---|---|---|
1 mM | 1.851 ml | 9.257 ml | 18.514 ml |
5 mM | 0.37 ml | 1.851 ml | 3.703 ml |
10 mM | 0.185 ml | 0.926 ml | 1.851 ml |
5 mM | 0.037 ml | 0.185 ml | 0.37 ml |
biological activity | BAI1 is a direct allosteric inhibitor of BAX with a Kd of 15.0±4 μm. |
Target | Value |
Bax (Cell-free assay) | 15.0 μM(Kd) |
Cell Line: | Mouse MEF |
Concentration: | 0.3125 μM , 0.625 μM, 1 μM, 1.25 μM, 1.5 μM, 2.5 μM , 3 μM, 4 μM, 5 4 μM, 10 4 μM |
Incubation Time: | 8 hours |
Result: | Inhibited cell death in BAX-dependent manner. |