BAY-57-1293

Name	BAY 57-1293
Synonyms	AIC316 Pritelivir PRITELIVIR BAY 57-1293 BAY-57-1293 BAY571293(Pritelivir) 2-METHYL-2-PROPANYL [4-(CHLOROSULFONYL)PHENYL]CARBAMATE Benzeneacetamide, N-[5-(aminosulfonyl)-4-methyl-2-thiazolyl]-N-methyl-4-(2-pyridinyl)- N-[5-(Aminosulfonyl)-4-methyl-1,3-thiazol-2-yl]-N-methyl-2-[4-(2-pyridinyl)phenyl]acetamide BAY57-1293 Pritelivir
CAS	348086-71-5

Molecular Formula	C18H18N4O3S2
Molar Mass	402.49
Density	1.396±0.06 g/cm3(Predicted)
Boling Point	639.4±65.0 °C(Predicted)
pKa	9.31±0.60(Predicted)
Storage Condition	2-8°C(protect from light)
In vitro study	The mechanism of action was that BAY57-1293 directly inhibited the ATPase activity of the helicase-trigger complex by Virus in a dose-dependent manner. BAY 57-1293 also exhibited potent antiviral activity against acyclovir-resistant HSV mutants. BAY 57-1293 reduces Aβ caused by herpes simplex type 1 in vero cells by Virus and P-tau.
In vivo study	BAY57-1293 (oral) in mice and rats lethally disseminated herpes pathogenesis model (0.5 mg/kg), mouse herpes zoster-like skin disease spread model (15 mg/kg), and the mouse ocular herpes model showed strong antiviral activity.

Last Update：2024-01-02 23:10:35

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Product Name: BAY 57-1293 Visit Supplier Webpage Request for quotation
CAS: 348086-71-5
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409

Wechat: 18301782025

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BAY-57-1293

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