BCH001 - Names and Identifiers
BCH001 - Physico-chemical Properties
Molecular Formula | C20H15F3N2O5
|
Molar Mass | 420.34 |
Density | 1.448±0.06 g/cm3(Predicted) |
Boling Point | 494.3±45.0 °C(Predicted) |
Solubility | DMSO: 84 mg/mL (199.84 mM)( < 1 mg/ml refers to the product slightly soluble or insoluble) |
pKa | 3.39±0.36(Predicted) |
Storage Condition | -20℃ |
Use | BCH001 is a specific PAPD5 inhibitor that restored telomerase activity and telomere length in DC patient induced pluripotent stem cells. |
Target | PAPD5 |
BCH001 - Reference
Reference Show more | 1: Nagpal N, Wang J, Zeng J, Lo E, Moon DH, Luk K, Braun RO, Burroughs LM, Keel SB, Reilly C, Lindsley RC, Wolfe SA, Tai AK, Cahan P, Bauer DE, Fong YW, Agarwal S. Small-Molecule PAPD5 Inhibitors Restore Telomerase Activity in Patient Stem Cells. Cell Stem Cell. 2020 Jun 4;26(6):896-909.e8. doi: 10.1016/j.stem.2020.03.016. Epub 2020 Apr 21. PMID: 32320679; PMCID: PMC7275922. |
BCH001 - Preparation solution concentration reference
| 1mg | 5mg | 10mg |
---|
1 mM | 2.379 ml | 11.895 ml | 23.79 ml |
5 mM | 0.476 ml | 2.379 ml | 4.758 ml |
10 mM | 0.238 ml | 1.19 ml | 2.379 ml |
5 mM | 0.048 ml | 0.238 ml | 0.476 ml |
Last Update:2024-01-02 23:10:35
BCH001 - Introduction
2-((3-(ethoxycarbonyl)-6-(trifluoromethoxy)quinolin-4-yl)amino) benzic acid is a chemical substance, its properties, uses, preparation methods and safety information are as follows:
Properties: 2-((3-(ethoxycarbonyl)-6-(trifluoromethoxy)quinolin-4-yl)amino) benzic acid is an organic compound, which may have various properties, therefore, the specific properties should be determined according to the specific chemical structure. In general, it may be a solid, liquid or gas with a specific melting point, boiling point and solubility.
Uses: 2-((3-(ethoxycarbonyl)-6-(trifluoromethoxy)quinolin-4-yl)amino) benzic acid may have a variety of uses, including as a pharmaceutical intermediate, catalysts, dyes or solvents for organic synthesis. The particular application will depend on its chemical structure and properties.
Preparation method: 2-((3-(ethoxycarbonyl)-6-(trifluoromethoxy)quinolin-4-yl)amino) benzic acid can be prepared by various methods, the specific preparation method will depend on its chemical structure. In general, it can be synthesized by organic synthesis methods, including the formation of carbon-hydrogen bonds, substitution reactions, reduction reactions, etc.
Safety information: 2-((3-(ethoxycarbonyl)-6-(trifluoromethoxy)quinolin-4-yl)amino) the safety information of benzoic acid needs to be evaluated according to the specific chemical structure and properties. In General, necessary safety measures should be taken when handling 2-((3-(ethoxycarbonyl)-6-(trifluoromethoxy)quinolin-4-yl)amino) benzic acid, if appropriate protective equipment (such as gloves, goggles and gowns) is worn, work in a well-ventilated area and follow chemical-related operating instructions. Meanwhile, it is recommended to read its safety data sheet (SDS) carefully before using 2-((3-(ethoxycarbonyl)-6-(trifluoromethoxy)quinolin-4-yl)amino)benzoic acid or consult relevant professionals to ensure safe use and handling.
Last Update:2024-04-09 20:49:11