Molecular Formula | C7H11ClN2O |
Molar Mass | 174.63 |
Melting Point | 86-88°C(lit.) |
Boling Point | 208.5°C at 760 mmHg |
Flash Point | 79.9°C |
Water Solubility | soluble |
Solubility | H2O: soluble50mg/mL, clear to slightly hazy, colorless to faintly yellow |
Vapor Presure | 0.213mmHg at 25°C |
Appearance | White fine crystalline powder |
Color | White to off-white |
BRN | 3594959 |
PH | 5 (50g/l, H2O, 20℃) |
Storage Condition | 2-8°C |
Sensitive | Hygroscopic |
MDL | MFCD00066285 |
Use | Peptidase inhibitor (Peptidase inhibitor). Benzamidine hydrochloride is a reversible inhibitor of trypsin, tryptase and serine protease. A concentration of about 1 mM can be used for general protease inhibition. In order to inhibit yeast protease, a concentration in the range of 0.5 - 4.0 mM can be used. It can be exchanged with pepsin inhibitor (pepstatin A) to a large extent. In addition to being a competitive substance as a powerful trypsin inhibitor, benzamidine hydrochloride has also been proved to be a powerful competitive inhibitor of thrombin and plasmin (thrombin and plasmin). It has also been found that benzamidine hydrochloride as aprotinin can effectively prevent pancreatic hyperglycemia in degenerating human plasma |
Hazard Symbols | Xi - Irritant |
Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S37/39 - Wear suitable gloves and eye/face protection |
WGK Germany | 3 |
RTECS | CV6260000 |
FLUKA BRAND F CODES | 3-21 |
TSCA | Yes |
HS Code | 2925 29 00 |
use | peptidase inhibitor (Peptidase inhibitor). Benzamidine hydrochloride is a reversible inhibitor of trypsin, tryptase and serine protease. A concentration of about 1 mM can be used for general protease inhibition. In order to inhibit yeast protease, a concentration in the range of 0.5 - 4.0 mM can be used. It can be exchanged with pepsin inhibitor (pepstatin A) to a large extent. In addition to being a competitive substance as a powerful trypsin inhibitor, benzamidine hydrochloride has also been proved to be a powerful competitive inhibitor of thrombin and plasmin (thrombin and plasmin). It has also been found that benzamidine hydrochloride as aprotinin can effectively prevent the degradation of glucagon in degraded human plasma. |