Name | Benzenesulfonamide |
Synonyms | CL160 Benzenesulfomide Benzosuifqnamide BENZENESULFONAMIDE Benzenesulfonamide Benzenesulphonamide Benzene Sulfonamide BENZENESULPHONAMIDE Benzene sulfonamtde BENZENESULFONYLAMIDE |
CAS | 98-10-2 |
EINECS | 202-637-1 |
InChI | InChI=1/C6H7NO2S/c7-10(8,9)6-4-2-1-3-5-6/h1-5H,(H2,7,8,9) |
InChIKey | KHBQMWCZKVMBLN-UHFFFAOYSA-N |
Molecular Formula | C6H7NO2S |
Molar Mass | 157.19 |
Density | 1.274 (estimate) |
Melting Point | 149-152 °C (lit.) |
Boling Point | 315.5±25.0 °C(Predicted) |
Flash Point | 250°C |
Water Solubility | 4.3 g/L (16 ºC) |
Solubility | Soluble in methanol 25mg/ml |
Appearance | White or white-like crystalline powder |
Color | White to off-white |
BRN | 1100566 |
pKa | 10.1(at 25℃) |
Storage Condition | Store below +30°C. |
Refractive Index | 1.5500 (estimate) |
MDL | MFCD00007930 |
Physical and Chemical Properties | Monoclinic needle-like or plate-like crystals. Melting point 156 ℃(147-148 ℃), difficult to dissolve in water, soluble in ethanol, ether. Soluble in alkali. |
Use | Organic Synthesis, pharmaceutical intermediates. |
Hazard Symbols | Xn - Harmful |
Risk Codes | 22 - Harmful if swallowed |
Safety Description | 36 - Wear suitable protective clothing. |
WGK Germany | 3 |
RTECS | DA9380000 |
TSCA | Yes |
HS Code | 29350090 |
Toxicity | LD50 orally in Rabbit: 991 mg/kg |
Reference Show more | 1. Zhang, Fangmei, et al. "Enzymatic determination of uric acid using water-soluble CuInS/ZnS quantum dots as a fluorescent probe." Microchimica Acta 185.11 (2018): 1-8.https://doi.org/10.1007/s00604-018-3030-0 2. Zhang, Fangmei, et al. "Enzymatic determination of uric acid using water-soluble CuInS/ZnS quantum dots as a fluorescent probe." Microchimica Acta 185.11 (2018): 1-8.https://doi.org/10.1007/s00604-018-3030-0 3. [IF=4.411] Yuai Zhang et al."Interactions between Human Serum Albumin and Sulfadimethoxine Determined Using Spectroscopy and Molecular Docking."Molecules. 2022 Jan;27(5):1526 |
NIST chemical information | information provided by: webbook.nist.gov (external link) |
EPA chemical substance information | information provided by: ofmpeb.epa.gov (external link) |
biological activity | Benzenesulfonamide is an inhibitor of carbonic anhydrase. |
Target | Value |
Use | organic synthesis, pharmaceutical intermediates. used in organic synthesis and pharmaceutical industry |
production method | is obtained by amination of benzenesulfonyl chloride. |
category | toxic substances |
toxicity grade | poisoning |
Acute toxicity | oral-rat LD50: 991 mg/kg; Oral-mouse LD50: 740 mg/kg |
flammability hazard characteristics | flammability; Toxic nitrogen oxide and sulfur oxide fumes from combustion |
storage and transportation characteristics | ventilation and low temperature drying |
fire extinguishing agent | dry powder, foam, sand, carbon dioxide, water mist |