BENZYLIDENE-4-HYDROXYACETOPHENONE
4-Hydroxychalcone
CAS: 20426-12-4
Molecular Formula: C15H12O2
BENZYLIDENE-4-HYDROXYACETOPHENONE - Names and Identifiers
| Name | 4-Hydroxychalcone |
| Synonyms | 4-HYDROXYCHALCONE 4-Hydroxychalcone HYDROXYCHALCONE, 4- 2-(4-HYDROXYBENZAL)ACETOPHENONE 4-HYDROXYBENZYLIDENEACETOPHENONE 4-Hydroxybenzylideneacetophenone BENZYLIDENE-4-HYDROXYACETOPHENONE 2-(4-HYDROXYBENZYLIDENE)ACETOPHENONE 3-(4-hydroxyphenyl)-1-phenylprop-2-en-1-one 1-Phenyl-3-(4-hydroxyphenyl)-2-propene-1-one (E)-3-(4-HYDROXYPHENYL)-1-PHENYLPROP-2-EN-1-ONE (2E)-3-(4-hydroxyphenyl)-1-phenylprop-2-en-1-one |
| CAS | 20426-12-4 |
| EINECS | 622-377-6 |
| InChI | InChI=1/C15H12O2/c16-14-9-6-12(7-10-14)8-11-15(17)13-4-2-1-3-5-13/h1-11,16H/b11-8+ |
BENZYLIDENE-4-HYDROXYACETOPHENONE - Physico-chemical Properties
| Molecular Formula | C15H12O2 |
| Molar Mass | 224.25 |
| Density | 1.191±0.06 g/cm3(Predicted) |
| Melting Point | 180-184 °C |
| Boling Point | 394.9±34.0 °C(Predicted) |
| Flash Point | 168.6°C |
| Water Solubility | Insoluble in water. |
| Vapor Presure | 8.41E-07mmHg at 25°C |
| BRN | 2049155 |
| pKa | 9.76±0.26(Predicted) |
| Refractive Index | 1.653 |
BENZYLIDENE-4-HYDROXYACETOPHENONE - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S37/39 - Wear suitable gloves and eye/face protection S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
| UN IDs | UN 3077 9/PG III |
| RTECS | UD1675000 |
| HS Code | 29144090 |
| Hazard Class | 9 |
| Packing Group | III |
BENZYLIDENE-4-HYDROXYACETOPHENONE - Reference Information
| biological activity | 4-Hydroxychalcone is a chalcone metabolite with anti-angiogenesis and anti-inflammatory effects. 4-Hydroxychalcone inhibits angiogenesis by inhibiting the growth factor pathway without signs of cytotoxicity. 4-Hydroxychalcone inhibits TNF-α-induced activation of the NF-κB pathway and activates BMP signaling, reducing resistant hypertension (RH) by attenuating aldosteronism and renal damage in mice. |
| target | TargetValue NF-κB () |
| Target | Value |
Last Update：2024-04-09 15:16:38
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Product Name: 2-(4-Hydroxybenzal)Acetophenone Visit Supplier Webpage Request for quotationCAS: 20426-12-4
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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