Name | Nα-(Benzyloxycarbonyloxy) Succinimide |
Synonyms | Z-OSu Z-ONSu CBZ-OSU CBZ-ONSU BENZYLOXYCARBONYLSUCCINIMIDE benzyl succinimido carbonate BENZYLOXYCARBONYLOXYSUCCINIMIDE BENZYL N-SUCCINIMIDYL CARBONATE BENZYLOXYLCARBONYLOXYSUCCINIMIDE N-(Benzyloxycarbonyloxy)succinimide N-(Benzyloxycarbonyloxy) Succinimide Nα-(Benzyloxycarbonyloxy) Succinimide BENZYLOXYCARBONYL-N-HYDROXYSUCCINIMIDE O-Benzyloxycarbonyl-N-hydroxysuccinimide 1-{[(benzyloxy)carbonyl]oxy}pyrrolidine-2,5-dione |
CAS | 13139-17-8 |
EINECS | 236-075-3 |
InChI | InChI=1/C12H11NO5/c14-10-6-7-11(15)13(10)18-12(16)17-8-9-4-2-1-3-5-9/h1-5H,6-8H2 |
Molecular Formula | C12H11NO5 |
Molar Mass | 249.22 |
Density | 1.3189 (rough estimate) |
Melting Point | 80-82°C(lit.) |
Boling Point | 392.32°C (rough estimate) |
Flash Point | 81°C |
Solubility | acetone: 0.1g/mL, clear |
Vapor Presure | 1.23E-05mmHg at 25°C |
Appearance | White crystalline powder |
Color | White to off-white |
BRN | 1387927 |
Storage Condition | Keep in dark place,Inert atmosphere,2-8°C |
Stability | Stable. Moisture sensitive. |
Sensitive | Moisture Sensitive |
Refractive Index | 1.5560 (estimate) |
MDL | MFCD00005513 |
Physical and Chemical Properties | Melting point 80-82°C DECOMPOSITION 81°C |
Use | Used as a polypeptide reagent |
Risk Codes | R43 - May cause sensitization by skin contact R24/25 - R36/37/38 - Irritating to eyes, respiratory system and skin. R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. |
Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. S36 - Wear suitable protective clothing. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
WGK Germany | 3 |
FLUKA BRAND F CODES | 8-10 |
HS Code | 29252900 |
Decomposition | 81 ºC |
Use | Benzoxycarbonyl succinimide is a peptide precursor reagent used to prepare peptide thioacid. It is also used to prepare aminoglycoside derivatives, which have the function of topoisomerase and have inhibitory effects on both humans and bacteria. Used as polypeptide reagent Selective introduction of Z-amino protective reagent in the synthesis of amino acids and aminoglycoside antibiotics |