BI3812
BI-3812
CAS: 2166387-64-8
Molecular Formula: C26H32ClN7O5
BI3812 - Names and Identifiers
BI3812 - Physico-chemical Properties
| Molecular Formula | C26H32ClN7O5 |
| Molar Mass | 558.03 |
| Density | 1.40±0.1 g/cm3(Predicted) |
| Solubility | DMSO : 20.83 mg/mL (37.33 mM; Need ultrasonic);H2O : < 0.1 mg/mL (insoluble) |
| pKa | 14.73±0.46(Predicted) |
| Storage Condition | -20°C |
| In vivo study | BI-3812 is a BCL6 inhibitor, with an IC 50 of ≤3 nM. BI-3812 shows an IC 50 of 40 nM for the cellular BCL6. |
BI3812 - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 1.792 ml | 8.96 ml | 17.92 ml |
| 5 mM | 0.358 ml | 1.792 ml | 3.584 ml |
| 10 mM | 0.179 ml | 0.896 ml | 1.792 ml |
| 5 mM | 0.036 ml | 0.179 ml | 0.358 ml |
Last Update：2024-01-02 23:10:35
BI3812 - Introduction
BI-3812 is an organic compound with the chemical structure [(3-chlorophyll) dimethylsilanolate]dihydrogen Phosphatate.
Nature:
1. Appearance: the BI-3812 is colorless or light yellow liquid;
2. Density: about 1.16 g/mL;
3. Melting Point: About -30 ℃;
4. Boiling point: About 175 ℃;
5. At room temperature can be dissolved in organic solvents, such as ethers, ketones and aromatic hydrocarbons, but insoluble in water.
Use:
BI-3812 is mainly used as a catalyst in organic synthesis. It can play an important role in the carbon-hydrogen bond functionalization reaction, promote the reaction and improve the yield. In addition, it can also be used to catalyze the interconversion of functional groups such as ethers and alcohols.
Preparation Method:
BI-3812 is usually prepared by reacting a mixture of 3-chlorobenzyl alcohol and dimethylaminoethyldiethanolamine with Tri (O-phenyl) phosphate at room temperature. The product of the reaction is cracked, filtered and distilled to obtain pure BI-3812.
Safety Information:
1. BI-3812 are organic compounds and should be operated in a well-ventilated place and avoid prolonged exposure to the air;
2. Contact with BI-3812 may cause eye and skin irritation, so use should wear goggles and protective gloves;
3. Seek immediate medical help if BI-3812 is ingested or inhaled;
4. BI-3812 should be stored in a dry, cool place, away from fire and other flammable materials.
Nature:
1. Appearance: the BI-3812 is colorless or light yellow liquid;
2. Density: about 1.16 g/mL;
3. Melting Point: About -30 ℃;
4. Boiling point: About 175 ℃;
5. At room temperature can be dissolved in organic solvents, such as ethers, ketones and aromatic hydrocarbons, but insoluble in water.
Use:
BI-3812 is mainly used as a catalyst in organic synthesis. It can play an important role in the carbon-hydrogen bond functionalization reaction, promote the reaction and improve the yield. In addition, it can also be used to catalyze the interconversion of functional groups such as ethers and alcohols.
Preparation Method:
BI-3812 is usually prepared by reacting a mixture of 3-chlorobenzyl alcohol and dimethylaminoethyldiethanolamine with Tri (O-phenyl) phosphate at room temperature. The product of the reaction is cracked, filtered and distilled to obtain pure BI-3812.
Safety Information:
1. BI-3812 are organic compounds and should be operated in a well-ventilated place and avoid prolonged exposure to the air;
2. Contact with BI-3812 may cause eye and skin irritation, so use should wear goggles and protective gloves;
3. Seek immediate medical help if BI-3812 is ingested or inhaled;
4. BI-3812 should be stored in a dry, cool place, away from fire and other flammable materials.
Last Update：2024-04-09 20:52:54
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Product Name: BI-3812 Visit Supplier Webpage Request for quotation
CAS: 2166387-64-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 2166387-64-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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