BOC-2-AMINOACETONITRILE

BOC-2-AMINOACETONITRILE - Names and Identifiers

Name	N-(tert-butoxycarbonyl)-2-aminoaceto-nitrile
Synonyms	AKOS 91568 BOC-GLY-NITRILE BOC-2-AMINOACETONITRILE N-BOC-2-Aminoacetonitrile N-(TERT-BUTOXYCARBONYL)-2-AMINOACETONITRILE N-(tert-Butoxycarbonyl)-2-aminoacetonitrile N-(tert-butoxycarbonyl)-2-aminoaceto-nitrile N-(cyanomethyl)carbamic acid tert-butyl ester Carbamic acid, (cyanomethyl)-, 1,1-dimethylethyl ester Carbamic acid, (cyanomethyl)-, 1,1-dimethylethyl ester (9CI)
CAS	85363-04-8

BOC-2-AMINOACETONITRILE - Physico-chemical Properties

Molecular Formula	C7H12N2O2
Molar Mass	156.18
Density	1.1832 (rough estimate)
Melting Point	53-57°C(lit.)
Boling Point	186°C(lit.)
Flash Point	>230°F
pKa	9.96±0.46(Predicted)
Storage Condition	Keep in dark place,Sealed in dry,Room Temperature
Refractive Index	1.4880 (estimate)
MDL	MFCD00239390

BOC-2-AMINOACETONITRILE - Risk and Safety

Hazard Symbols	Xn - Harmful
Risk Codes	20/21/22 - Harmful by inhalation, in contact with skin and if swallowed.
Safety Description	36 - Wear suitable protective clothing.
WGK Germany	3

BOC-2-AMINOACETONITRILE - Introduction

N-(tert-butoxycarbonyl)-2-aminoaceto-nitrile is an organic compound with the chemical formula C8H13N3O2.

Nature:
N-(tert-butoxycarbonyl)-2-aminoaceto-nitrile is a white crystalline solid with a high melting point and boiling point. It is stable at room temperature, insoluble in water, but soluble in organic solvents such as chloroform and ethanol.

Use:
N-(tert-butoxycarbonyl)-2-aminoaceto-nitrile is a commonly used intermediate in drug synthesis. It can be used to synthesize various anticancer drugs, antibiotics, antiviral drugs, etc., and can also be used to synthesize amino acids and peptides.

Preparation Method:
the preparation method of N-(tert-butoxycarbonyl)-2-aminoaceto-nitrile is relatively simple, generally by reacting tert-butyl chloroformate with 2-amino acetonitrile.

Safety Information:
N-(tert-butoxycarbonyl)-2-aminoaceto-nitrile is an organic compound, and attention should be paid to safe operation. It may be irritating to the eyes, skin and respiratory tract, so wear appropriate protective equipment such as gloves, goggles and protective masks during operation. At the same time, it is necessary to ensure that the operation is carried out in a well-ventilated place to avoid inhalation of its vapors. If it comes into contact with skin or eyes, rinse immediately with plenty of water and seek medical help.

Last Update：2024-04-09 21:11:58