BOC-D-PHE-OL - Names and Identifiers
Name | N-Boc-D-Phenylalaninol
|
Synonyms | BOC-D-P BOC-D-PHE-OL BOC-D-PHENYLALANINOL N-Boc-D-Phenylalaninol N-T-BOC-D-PHENYLALANIOL N-T-BOC-D-PHENYLALANINOL D-(+)-BOC-PHENYLALANINOL tert-Butyl [(1R)-1-Benzyl-2-hydrox BOC-(R)-2-AMINO-3-PHENYL-1-PROPANOL tert-butyl [(1R)-1-benzyl-2-hydroxyethyl]carbamate tert-butyl [(1S)-1-benzyl-2-hydroxyethyl]carbamate (2R)-N-tert-Butoxycarbonyl-1-hydroxy-3-phenyl-2-propanaMine N-[(1R)-1-(HydroxyMethyl)-2-phenylethyl]carbaMic Acid 1,1-DiMethylethyl Ester CARBAMIC ACID, [(1R)-1-(HYDROXYMETHYL)-2-PHENYLETHYL]-, 1,1-DIMETHYLETHYL ESTER CARBAMIC ACID, [1-(HYDROXYMETHYL)-2,2-DIPHENYLETHYL]-,1,1-DIMETHYLETHYL ESTER, (R)- N-Boc-D-phenylalaninol
(R)-2-(tert-Butoxycarbonylamino)-3-phenyl-1-propanol
(R)-2-(Boc-amino)-3-phenyl-1-propanol
|
CAS | 106454-69-7
|
EINECS | 1533716-785-6 |
InChI | InChI=1/C14H21NO3/c1-14(2,3)18-13(17)15-12(10-16)9-11-7-5-4-6-8-11/h4-8,12,16H,9-10H2,1-3H3,(H,15,17)/t12-/m1/s1 |
BOC-D-PHE-OL - Physico-chemical Properties
Molecular Formula | C14H21NO3
|
Molar Mass | 251.32 |
Density | 1.0696 (rough estimate) |
Melting Point | 95-98 °C (lit.) |
Boling Point | 394.48°C (rough estimate) |
Specific Rotation(α) | +24°(23℃, c=1, CHCl3) |
Flash Point | 201.8°C |
Vapor Presure | 1.84E-07mmHg at 25°C |
Appearance | Bright yellow crystal |
BRN | 4686134 |
pKa | 12.07±0.46(Predicted) |
Storage Condition | Sealed in dry,2-8°C |
Refractive Index | 1.5280 (estimate) |
MDL | MFCD00216472 |
Physical and Chemical Properties | Storage Conditions: 2-8 ℃ WGK Germany:3 |
BOC-D-PHE-OL - Risk and Safety
Safety Description | 24/25 - Avoid contact with skin and eyes.
|
WGK Germany | 3 |
FLUKA BRAND F CODES | 9-21 |
HS Code | 29225090 |
BOC-D-PHE-OL - Introduction
N-Boc-D-Phenylalaninol is a compound whose chemical name is N-Boc-D-phenylalaninol. It is a white solid with low solubility at room temperature.
N-Boc-D-phenylalaninol is mainly used for special reactions in organic synthesis, such as acting as a catalyst in the synthesis of ammonia heterocycles. It can be used as a pharmaceutical intermediate for the synthesis of building blocks of drug molecules. In addition, N-Boc-D-phenylalaninol can also be used as a synthetic intermediate of chiral drugs.
The method for preparing N-Boc-D-phenylalaninol is usually achieved by introducing a protecting group into D-phenylalanine. First, D-phenylalanine was reacted with Boc anhydride, Boc protecting group was introduced, and then reduction reaction was carried out to obtain N-Boc-D-phenylalaninol.
Regarding safety information, N-Boc-D-Phenylalaninol is a chemical and care should be taken to prevent it from contacting the skin and eyes. During the operation, pay attention to follow the correct laboratory practice and use of personal protective equipment.
Last Update:2024-04-09 20:02:46