BOC-HIS(BOC)

BOC-HIS(BOC) - Names and Identifiers

Name	N,N'-Di-tert-butoxycarbonyl-L-histidine
Synonyms	BOC-HIS(BOC) Boc-His(Boc)-OH BOC-HIS(BOC)-OH N,1-Bis-Boc-L-histidine Boc-His(Boc)-OH·Benzene BOC-HIS(BOC)-OH BENZENE BOC-L-HIS(BOC)-OH BENZENE BOC-HISTIDINE(BOC)-OH BENZENE N,N'-Di-tert-butoxycarbonyl-L-histidine N,1-bis(tert-butoxycarbonyl)-L-histidine N ALPHA,N(IM)-DI-T-BUTOXYCARBONYL-L-HISTIDINE NALPHA,N(IM)-DI-TERT-BUTOXYCARBONYL-L-HISTIDINE N-ALPHA-TERT-BUTYLOXYCARBONYL-N-IM-TERT-BUTYLOXYCARBONYL-L-HISTIDINE BENZENE (S)-3-(1-(tert-Butoxycarbonyl)-1H-imidazol-4-yl)-2-(tert-butoxycarbonylamino)propanoic acid
CAS	20866-46-0
InChI	InChI=1/C16H25N3O6/c1-15(2,3)24-13(22)18-11(12(20)21)7-10-8-19(9-17-10)14(23)25-16(4,5)6/h8-9,11H,7H2,1-6H3,(H,18,22)(H,20,21)/t11-/m0/s1

BOC-HIS(BOC) - Physico-chemical Properties

Molecular Formula	C16H25N3O6
Molar Mass	355.39
Density	1.22±0.1 g/cm3(Predicted)
pKa	3.10±0.10(Predicted)
Storage Condition	Sealed in dry,Room Temperature
Refractive Index	1.533

BOC-HIS(BOC) - Introduction

N,N'-Di-tert-butoxycarbonyl-L-histidine, chemical name N,N'-di-tert-butoxycarbonyl-L-histidine, is an amino acid protecting group. The following is a description of its nature, use, preparation and safety information:

Nature:
N,N'-Di-tert-butoxycarbonyl-L-histidine is a white crystalline solid with a molecular formula of C17H28N4O5 and a molecular weight of 372.43g/mol. It is stable at room temperature and has good solubility.

Use:
N,N'-Di-tert-butoxycarbonyl-L-histidine are mainly used as protecting groups for amino acids in organic synthesis. It can protect the carboxyl and amino groups in amino acids to control the selectivity of chemical reactions and further modification.

Method:
The preparation of N,N'-Di-tert-butoxycarbonyl-L-histidine can be obtained by reacting L-histidine with di-tert-butyldicarboximide in a suitable solvent. During the reaction, attention should be paid to the control of temperature and reaction time.

Safety Information:
N,N'-Di-tert-butoxycarbonyl-L-histidine is a chemical and should be handled in accordance with laboratory safety practices. Avoid direct contact with skin and eyes. Proper protective gloves and glasses should be worn during use. If accidentally inhaled or ingested, should be timely medical treatment. Detailed safety information can be found in the relevant safety data sheets.

Last Update：2024-04-10 22:29:15

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