BOC-HOMOARGININE(NO2)-OH - Names and Identifiers
Name | Boc-Homoarg(NO2)-OH
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Synonyms | BOC-HAR(NO2)-OH Boc-HoArg(NO2)-OH BOC-HOARG(NO2)-OH BOC-HOMOARG(NO2)-OH Boc-Homoarg(NO2)-OH Boc-HomoArg(NO2)-OH HCl Boc-HomoArg(NO2)-OH.HCl BOC-HOMOARGININE(NO2)-OH boc-homoarg(no2)-OH.HClmin Boc-N'-Nitro-L-Homoarginine BOC-N-OMEGA-(NITRO)-L-HOMOARGININE N-ALPHA-T-BUTOXYCARBONYL-N-G-NITRO-L-HOMOARGININE (2S)-2-(tert-butoxycarbonylamino)-6-[(N-nitrocarbamimidoyl)amino]hexanoic acid
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CAS | 28968-64-1
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InChI | InChI=1/C12H23N5O6/c1-12(2,3)23-11(20)15-8(9(18)19)6-4-5-7-14-10(13)16-17(21)22/h8H,4-7H2,1-3H3,(H,15,20)(H,18,19)(H3,13,14,16)/t8-/m0/s1 |
BOC-HOMOARGININE(NO2)-OH - Physico-chemical Properties
Molecular Formula | C12H23N5O6
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Molar Mass | 333.34 |
Density | 1.37±0.1 g/cm3(Predicted) |
pKa | 3.85±0.50(Predicted) |
Storage Condition | Sealed in dry,2-8°C |
Refractive Index | 1.558 |
BOC-HOMOARGININE(NO2)-OH - Introduction
Boc-Homoarg(NO2)-OH(Boc-Homoarg(NO2)-OH) is an organic compound whose structure contains the side chain of the amino acid homoarginine with a Nitro substituent. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: White crystal or crystalline powder
-Solubility: Soluble in some organic solvents such as dimethyl sulfoxide (DMSO) and dichloromethane (DCM), insoluble in water
-Melting point: About 120-122 ° C
-Molecular weight: about 300g/mol
Use:
- Boc-Homoarg(NO2)-OH is often used in the peptide synthesis process in organic synthesis as a synthetic intermediate
-It can generate N'-nitro-L-homoarginine (Homoarg(NO2)-OH) through deprotection reaction, thereby introducing nitro groups into the synthetic peptide chain
Method:
- Boc-Homoarg(NO2)-OH can be prepared by a variety of synthetic methods, the common method is obtained by the reaction of Boc-protected homoarginine with nitric acid
Safety Information:
-Since the compound is an intermediate compound commonly used in the laboratory, attention should be paid to correct operation and Laboratory Safety specifications
- Boc-Homoarg(NO2)-OH may be irritating to the eyes, skin and respiratory system and should be avoided
-Wear appropriate protective gloves, goggles, protective masks and other personal protective equipment during operation, and ensure that the operation is carried out in a well-ventilated Laboratory
-During storage, it should be kept dry and sealed, away from fire and oxidizing agents.
Last Update:2024-04-09 21:04:16