BOC-L-PRO-NITRILE
(R)-1-Boc-2-cyanopyrrolidine
CAS: 144688-70-0;228244-20-0
Molecular Formula: C10H16N2O2
BOC-L-PRO-NITRILE - Names and Identifiers
BOC-L-PRO-NITRILE - Physico-chemical Properties
| Molecular Formula | C10H16N2O2 |
| Molar Mass | 196.25 |
| Density | 1.08±0.1 g/cm3(Predicted) |
| Melting Point | 32-37℃ |
| Boling Point | 307.9±35.0 °C(Predicted) |
| Flash Point | >110℃ |
| Vapor Presure | 0.000703mmHg at 25°C |
| pKa | -4.97±0.40(Predicted) |
| Storage Condition | 2-8°C |
| Sensitive | Moisture & Light Sensitive |
| Refractive Index | 1.488 |
| MDL | MFCD06411382 |
| Physical and Chemical Properties | WGK Germany:3 |
BOC-L-PRO-NITRILE - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | R22 - Harmful if swallowed R36/37/38 - Irritating to eyes, respiratory system and skin. R43 - May cause sensitization by skin contact |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
| WGK Germany | 3 |
| HS Code | 29339900 |
BOC-L-PRO-NITRILE - Introduction
(R)-1-Boc-2-cyanopyrrolidine is an organic compound whose chemical properties mainly include:
1. Structural characteristics: It is a chiral compound with (S)-and (R)-Two enantiomers. The molecule contains Boc protecting group (tert-butoxycarbonyl), cyano and pyrrole ring structure.
2. Physical properties:(R)-1-Boc-2-cyanopyrrolidine is colorless to white crystal or powder, soluble in most organic solvents, such as ether, methanol, etc.
3. Use: it is an important intermediate in the synthesis of organic compounds, commonly used in the preparation of drugs, pesticides and bioactive molecules. Its cyano group can be further reacted for the construction of carbon-carbon and carbon-nitrogen bonds, C- C and C- N building reactions.
4. Preparation method: mainly obtained by reaction of cyano group and Boc protecting group on pyrrole ring. (R)-1-Boc-2-cyanopyrrolidine can be obtained by reacting lithium cyanate with sodium cyanate at (-40°C) and then reacting with the Boc-OSuccinimid group.
1. Structural characteristics: It is a chiral compound with (S)-and (R)-Two enantiomers. The molecule contains Boc protecting group (tert-butoxycarbonyl), cyano and pyrrole ring structure.
2. Physical properties:(R)-1-Boc-2-cyanopyrrolidine is colorless to white crystal or powder, soluble in most organic solvents, such as ether, methanol, etc.
3. Use: it is an important intermediate in the synthesis of organic compounds, commonly used in the preparation of drugs, pesticides and bioactive molecules. Its cyano group can be further reacted for the construction of carbon-carbon and carbon-nitrogen bonds, C- C and C- N building reactions.
4. Preparation method: mainly obtained by reaction of cyano group and Boc protecting group on pyrrole ring. (R)-1-Boc-2-cyanopyrrolidine can be obtained by reacting lithium cyanate with sodium cyanate at (-40°C) and then reacting with the Boc-OSuccinimid group.
Last Update：2024-04-09 02:00:42
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Product Name: (R)-(+)-1-Boc-2-pyrrolidinecarbonitrile Visit Supplier Webpage Request for quotationCAS: 228244-20-0
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Multiple Specifications
Product Name: (R)-(+)-1-Boc-2-pyrrolidinecarbonitrile Visit Supplier Webpage Request for quotationCAS: 228244-20-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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