BOC-N-ME-PHE-OH

BOC-N-ME-PHE-OH - Names and Identifiers

Name	Boc-N-Me-Phe-OH
Synonyms	BOC-MEPHE-OH BOC-L-MEPHE-OH BOC-N-ME-PHE-OH Boc-N-Me-Phe-OH BOC-N-METHYL-L-PHE-OH BOC-N-ME-PHENYLALANINE Boc-N-methyl-L-phenylalanine BOC-N-METHYL-L-PHENYLALANINE BOC-N-ALPHA-METHYL-L-PHENYLALANINE N-(tert-Butoxycarbonyl)-N-methyl-L-phenylalanine N-(tert-butoxycarbonyl)-N-methyl-D-phenylalanine N-ALPHA-TERT-BUTYLOXYCARBONYL-N-ALPHA-METHYL-L-PHENYLALANINE
CAS	37553-65-4
InChI	InChI=1/C15H21NO4/c1-15(2,3)20-14(19)16(4)12(13(17)18)10-11-8-6-5-7-9-11/h5-9,12H,10H2,1-4H3,(H,17,18)/t12-/m1/s1

BOC-N-ME-PHE-OH - Physico-chemical Properties

Molecular Formula	C15H21NO4
Molar Mass	279.33
Density	1.146±0.06 g/cm3(Predicted)
Melting Point	168-170 °C
Boling Point	405.0±34.0 °C(Predicted)
Flash Point	198.8°C
Solubility	Chloroform (Slightly), Methanol (Slightly)
Vapor Presure	2.75E-07mmHg at 25°C
Appearance	Solid
Color	White to Off-White
BRN	2386503
pKa	3.90±0.10(Predicted)
Storage Condition	Sealed in dry,2-8°C
Refractive Index	1.529

BOC-N-ME-PHE-OH - Risk and Safety

WGK Germany	3
Hazard Class	IRRITANT

BOC-N-ME-PHE-OH - Introduction

Boc-N-Me-Phe-OH(Boc-N-Me-Phe-OH) is an organic compound, its molecular formula is C17H23NO4, the structure contains a protecting group (Boc group) and a methyl group, and the asparagine amino terminal (C terminal) of phenylalanine. The following is a description of the nature, use, preparation and safety information of the Boc-N-Me-Phe-OH:

properties: Boc-N-Me-Phe-OH is a white crystal or crystalline powder, its melting point is about 90-92 ℃. This compound is stable at room temperature, but is easily hydrolyzed under strong alkaline conditions.

Purpose: Boc-N-Me-Phe-OH is a commonly used amino protecting reagent, which can be used in organic synthesis. In the synthesis of polypeptides, methyl groups and protecting groups can be easily introduced by reaction with other amino acids and reactive groups. In addition, the compound is also useful as a reagent in the field of pharmaceutical research and chemical biology research.

preparation method: Boc-N-Me-Phe-OH can be prepared by L-phenylalanine and tert-butyl dimethyl amide compound reaction. First, L-phenylalanine is reacted with tert-butyl dicarboxamide ester (Boc-ON) to produce Boc-N-tert-butyl-L-phenylalanine, and then the tert-butyl group is removed with aqueous hydrochloric acid to produce the desired product.

Safety Information: Boc-N-Me-Phe-OH is generally stable and safe, but it may be irritating to the eyes, skin and respiratory system. During the operation, appropriate personal protective measures should be taken, such as wearing chemical goggles, laboratory gloves and protective clothing. At the same time, please make sure to operate under well-ventilated conditions to avoid inhaling dust or solutions. If the compound is exposed externally, rinse immediately with plenty of water and seek medical attention. During handling and storage, the safe handling of chemicals should be strictly followed.

Last Update：2024-04-09 21:11:58