BOC-N-METHYL-L-ILE-OH
Boc-N-Methyl-L-isoleucine
CAS: 52498-32-5
Molecular Formula: C12H23NO4
BOC-N-METHYL-L-ILE-OH - Names and Identifiers
| Name | Boc-N-Methyl-L-isoleucine |
| Synonyms | BOC-MEILE-OH BOC-MELLE-OH BOC-L-MEILE-OH Boc-N-Me-Ile-OH BOC-N-ME-ILE-OH BOC-N-ME-ISOLEUCINE BOC-N-METHYL-L-ILE-OH Boc-N-Methyl-L-isoleucine BOC-N-METHYL-L-ISOLEUCINE BOC-N-ALPHA-METHYL-L-ISOLEUCINE N-(tert-butoxycarbonyl)-N-methyl-L-isoleucine N-tert-Butyloxycarbonyl-N-methyl-L-isoleucine |
| CAS | 52498-32-5 |
| InChI | InChI=1/C12H23NO4/c1-7-8(2)9(10(14)15)13(6)11(16)17-12(3,4)5/h8-9H,7H2,1-6H3,(H,14,15)/t8-,9-/m0/s1 |
BOC-N-METHYL-L-ILE-OH - Physico-chemical Properties
| Molecular Formula | C12H23NO4 |
| Molar Mass | 245.32 |
| Density | 1.053±0.06 g/cm3(Predicted) |
| Boling Point | 338.2±21.0 °C(Predicted) |
| Flash Point | 158.3°C |
| Vapor Presure | 1.86E-05mmHg at 25°C |
| BRN | 4251277 |
| pKa | 4.05±0.22(Predicted) |
| Storage Condition | Sealed in dry,2-8°C |
| Refractive Index | 1.466 |
BOC-N-METHYL-L-ILE-OH - Risk and Safety
| WGK Germany | 3 |
BOC-N-METHYL-L-ILE-OH - Introduction
Boc-N-Methyl-L-isoleucine (Boc-N-Methyl-L-isoleucine) is an amino acid derivative. It has the following properties:
1. appearance: white or white solid.
2. solubility: soluble in some organic solvents, such as dimethyl sulfoxide and methanol, insoluble in water.
3. molecular formula: C13H25NO4.
4. Molecular weight: 259.34g/mol.
Boc-N-Methyl-L-isoleucine are widely used in pharmaceutical research, peptide synthesis and organic synthesis. It is often used as a building block for the synthesis of polypeptides or proteins. This is because it has a protecting group (Boc protecting group), which can protect the amino group in the amino acid, thereby improving the selectivity and efficiency in the synthesis.
The preparation of Boc-N-Methyl-L-isoleucine is usually carried out by the following steps:
1. Reaction of N-methyl-L-isoleucine with tert-butoxycarbonyl acid (BOC-acid) to produce Boc-N-Methyl-L-isoleucine.
2. The reaction is carried out using a solvent and a catalyst, usually an appropriate organic solvent such as dimethyl sulfoxide is selected, and a catalyst such as dimethyl sulfoxide or dimethylaminopyridine is added.
Regarding safety information, Boc-N-Methyl-L-isoleucine currently have no clear toxicity data reported. However, as any chemical, appropriate laboratory safety measures should be taken when handling, including wearing protective glasses and gloves, and handling in well-ventilated conditions. It should be stored properly and avoid contact with skin, eyes and respiratory tract. If necessary, refer to the relevant chemical safety data sheets (MSDS) and laboratory safety guidelines.
1. appearance: white or white solid.
2. solubility: soluble in some organic solvents, such as dimethyl sulfoxide and methanol, insoluble in water.
3. molecular formula: C13H25NO4.
4. Molecular weight: 259.34g/mol.
Boc-N-Methyl-L-isoleucine are widely used in pharmaceutical research, peptide synthesis and organic synthesis. It is often used as a building block for the synthesis of polypeptides or proteins. This is because it has a protecting group (Boc protecting group), which can protect the amino group in the amino acid, thereby improving the selectivity and efficiency in the synthesis.
The preparation of Boc-N-Methyl-L-isoleucine is usually carried out by the following steps:
1. Reaction of N-methyl-L-isoleucine with tert-butoxycarbonyl acid (BOC-acid) to produce Boc-N-Methyl-L-isoleucine.
2. The reaction is carried out using a solvent and a catalyst, usually an appropriate organic solvent such as dimethyl sulfoxide is selected, and a catalyst such as dimethyl sulfoxide or dimethylaminopyridine is added.
Regarding safety information, Boc-N-Methyl-L-isoleucine currently have no clear toxicity data reported. However, as any chemical, appropriate laboratory safety measures should be taken when handling, including wearing protective glasses and gloves, and handling in well-ventilated conditions. It should be stored properly and avoid contact with skin, eyes and respiratory tract. If necessary, refer to the relevant chemical safety data sheets (MSDS) and laboratory safety guidelines.
Last Update：2024-04-09 20:45:29
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CAS: 52498-32-5
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QQ: 3008007409
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CAS: 52498-32-5
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
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