Name | N-tert-Butoxycarbonyl-O-benzyl-L-tyrisine |
Synonyms | BOC-TYR(BZL) Boc-Tyr(Bzl)-OH BOC-TYR(BZL)-OH BOC-L-TYR(BZL)-OH BOC-O-BENZYL-L-TYR BOC-TYROSINE(BZL)-OH BOC-O-BENZYL-L-TYROSINE Boc-O-Benzyl-L-Tyrosine Butoxycarbonylbenzyltyrisine T-BUTYLOXYCARBONYL-O-BENZYL-L-TYROSINE N-T-boc-O-benzyl-L-tyrosine crystalline O-benzyl-N-(tert-butoxycarbonyl)tyrosine N-tert-Butoxycarbonyl-O-benzyl-L-tyrisine O-benzyl-N-(tert-butoxycarbonyl)-L-tyrosine N-alpha-t-butyloxycabonyl-O-benzyl-L-tyrosine BOC-(S)-2-AMINO-3-(4'-BENZYLOXYPHENYL)PROPANOIC ACID (2S)-3-[4-(benzyloxy)phenyl]-2-[(tert-butoxycarbonyl)amino]propanoate |
CAS | 2130-96-3 |
EINECS | 218-349-4 |
InChI | InChI=1/C21H25NO5/c1-21(2,3)27-20(25)22-18(19(23)24)13-15-9-11-17(12-10-15)26-14-16-7-5-4-6-8-16/h4-12,18H,13-14H2,1-3H3,(H,22,25)(H,23,24)/p-1/t18-/m0/s1 |
Molecular Formula | C21H25NO5 |
Molar Mass | 371.43 |
Density | 1.185±0.06 g/cm3(Predicted) |
Melting Point | 110-112°C |
Boling Point | 552.4±50.0 °C(Predicted) |
Specific Rotation(α) | 27 º (c=2% in ethanol) |
Flash Point | 287.9°C |
Solubility | almost transparency in EtOH |
Vapor Presure | 4.87E-13mmHg at 25°C |
Appearance | White crystalline powder |
Color | White |
BRN | 2227416 |
pKa | 2.99±0.10(Predicted) |
Storage Condition | Store below +30°C. |
Refractive Index | 29.5 ° (C=2, EtOH) |
MDL | MFCD00065597 |
Physical and Chemical Properties | White crystalline powder; Insoluble in water and petroleum ether, soluble in ethyl acetate and ethanol; mp is 110- 112 ℃; Specific optical rotation [α]20D 27 °(0.5-2.0 mg/ml, ethanol). |
Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. |
WGK Germany | 3 |
HS Code | 29242990 |
use | Boc-O-benzyl-L-tyrosine is used for biochemical reagents, amino acid protective monomers, etc. Used for polypeptide synthesis, used as amino acid protective monomer. |
Production method | Suspended O-benzyl-L-tyrosine in dioxane solution, acylated with tert-butoxycarbonyl azide to obtain a crude product, extracted with ethyl acetate at pH 9-10, and then refined by recrystallization. |