BOC-P-CHLORO-D-PHENYLALANINE - Names and Identifiers
BOC-P-CHLORO-D-PHENYLALANINE - Physico-chemical Properties
Molecular Formula | C14H18ClNO4
|
Molar Mass | 299.75 |
Density | 1.2167 (rough estimate) |
Melting Point | ~110°C |
Boling Point | 452.5±40.0 °C(Predicted) |
Specific Rotation(α) | -24 º (c=1,EtOH) |
Flash Point | 227.5°C |
Vapor Presure | 5.61E-09mmHg at 25°C |
Appearance | Powder |
Color | White |
BRN | 5381988 |
pKa | 3.83±0.10(Predicted) |
Storage Condition | Sealed in dry,2-8°C |
Refractive Index | 1.6800 (estimate) |
MDL | MFCD00076978 |
Physical and Chemical Properties | Melting point 108°C specific optical rotation -24 ° (c = 1,EtOH)
|
BOC-P-CHLORO-D-PHENYLALANINE - Risk and Safety
Hazard Symbols | Xi - Irritant
|
Safety Description | 24/25 - Avoid contact with skin and eyes.
|
WGK Germany | 3 |
HS Code | 29242990 |
Hazard Class | IRRITANT |
BOC-P-CHLORO-D-PHENYLALANINE - Introduction
(R)-N-BOC-4-Chlorophenylalanine, also known as (R)-N-BOC-4-Chlorophenylalanine, is an organic compound. The following is a description of its nature, use, preparation and safety information:
1. nature:
(R)-N-BOC-4-Chlorophenylalanine is a white crystalline solid stable at ambient temperatures. It has a protecting group BOC (bis (tert-butyloxycarbonyl) amino) and a chlorophenylalanine group. Its chemical formula is C15H18ClNO4 and its relative molecular mass is 303.76g/mol.
2. use:
(R)-N-BOC-4-Chlorophenylalanine is commonly used in peptide synthesis reactions in organic synthesis. It can be used as a starting material for peptide synthesis and for the synthesis of biologically active peptide chains. In addition, it can also be used in drug research and development, chemical biology research and other fields.
3. Preparation method:
(R)-N-BOC-4-Chlorophenylalanine can be prepared by reacting 4-chlorophenylalanine with BOC-NHS(N-bis (tert-butyloxycarbonyl) amino-N-hydroxysuccinimide). The specific step is to react 4-chlorophenylalanine with BOC-NHS under basic conditions to produce (R)-N-BOC-4-Chlorophenylalanine.
4. Safety Information:
(R)-N-BOC-4-Chlorophenylalanine is not currently classified as a particularly hazardous chemical. However, as a chemical, it should be handled in accordance with routine laboratory safety practices. During operation, attention should be paid to avoid direct contact with skin, eyes or respiratory tract, and maintain good ventilation. Always use personal protective equipment such as lab gloves, goggles, and laboratory clothing properly during handling.
Last Update:2024-04-09 20:45:29