BOC-PHE(F)3-OH

BOC-PHE(F)3-OH - Names and Identifiers

Name	N-(tert-butoxycarbonyl)-3,4,5-trifluoro-L-phenylalanine
Synonyms	BOC-PHE(F)3-OH BOC-PHE(M,P-F3)-OH Boc-Phe(3,4,5-TriF)-OH BOC-PHE(3,4,5-TRIFLUORO)-OH BOC-L-3,4,5-TRIFLUOROPHENYLALANINE Boc-L-3,4,5-Trifluorophenylalanine BOC-3,4,5-TRIFLUORO-L-PHENYLALANINE 3,4,5-TRIFLUORO-L-PHENYLALANINE BOC PROTECTED N-(tert-butoxycarbonyl)-3,4,5-trifluoro-L-phenylalanine N-(tert-Butoxycarbonyl)-3,4,5-trifluoro-L-phenylalanine, (2S)-2-[(tert-Butoxycarbonyl)amino]-3-(3,4,5-trifluorophenyl)propanoic acid
CAS	205445-54-1
InChI	InChI=1/C14H16F3NO4/c1-14(2,3)22-13(21)18-10(12(19)20)6-7-4-8(15)11(17)9(16)5-7/h4-5,10H,6H2,1-3H3,(H,18,21)(H,19,20)/t10-/m0/s1

BOC-PHE(F)3-OH - Physico-chemical Properties

Molecular Formula	C14H16F3NO4
Molar Mass	319.28
Density	1.323±0.06 g/cm3(Predicted)
Boling Point	424.4±45.0 °C(Predicted)
Flash Point	210.5°C
Vapor Presure	5.83E-08mmHg at 25°C
pKa	3.71±0.10(Predicted)
Storage Condition	Sealed in dry,2-8°C
Refractive Index	1.495

BOC-PHE(F)3-OH - Risk and Safety

Hazard Symbols	Xi - Irritant
Hazard Note	Harmful/Irritant/Keep Cold
Hazard Class	IRRITANT

BOC-PHE(F)3-OH - Introduction

N-(tert-butoxycarbonyl)-3,4, 5-trifluororo-L-Phenylalanine is an organic compound containing the amino acids alanine and phenyl and a trifluoromethyl group in its chemical structure.

The following are some properties of N-(tert-butoxycarbonyl)-3,4,5-trifluoro-L-phenylalanine:
-Appearance: generally colorless or white solid
-molecular formula: C14H13F3NO4
-Molecular weight: 321.25g/mol
-Melting point: About 120-125 ° C
-Solubility: Soluble in some organic solvents, such as dimethyl sulfoxide and dichloromethane

N-(tert-butoxycarbonyl)-3,4,5-trifluoro-L-Phenylalanine is mainly used in the field of organic synthesis as an important amino protecting group. It is often used in organic synthesis to protect amino groups to prevent non-selective reactions. Once a particular reaction is complete, the protecting group can be removed by appropriate deprotection conditions to expose the amino group that has not been reacted.

The preparation of N-(tert-butoxycarbonyl)-3,4,5-trifluoro-L-phenylalanine generally employs known synthetic methods. For example, first through the reaction of benzene chloride and trifluorobenzyl alcohol reaction, 3,4, 5-trifluorophenyl aldehyde, and then with alanine reaction to obtain N-(tert-butoxycarbonyl)-3,4,5-trifluoro-L-phenylalanine.

With regard to safety information, as with any organic compound, appropriate laboratory safety measures need to be taken when using N-(tert-butoxycarbonyl)-3,4,5-trifluoro-L-phenylalanine. This includes wearing appropriate personal protective equipment, such as lab gloves and eye protection. In addition, exposure to high temperatures, fire sources, and strong oxidants should be avoided. For detailed safety information on this compound, it is recommended to refer to the relevant safety data sheet.

Last Update：2024-04-10 22:29:15