Molecular Formula | C22H26N4O3 |
Molar Mass | 394.47 |
Density | 1.263±0.06 g/cm3(Predicted) |
Boling Point | 527.3±50.0 °C(Predicted) |
Solubility | DMSO: < 7.8 mg/mL |
pKa | 13.06±0.20(Predicted) |
Storage Condition | -20℃ |
In vitro study | GSK-5959 (3a) also displays selectivity over the closely related family members, BRPF2 (100-fold) and BRPF3 (>1000-fold). GSK-5959 (3a) exhibits an EC 50 = 0.98 μM) in cellular NanoBRET assay. GSK-5959 has no effect on TRIM24 SUMOylation. |
1mg | 5mg | 10mg | |
---|---|---|---|
1 mM | 2.535 ml | 12.675 ml | 25.351 ml |
5 mM | 0.507 ml | 2.535 ml | 5.07 ml |
10 mM | 0.254 ml | 1.268 ml | 2.535 ml |
5 mM | 0.051 ml | 0.254 ml | 0.507 ml |