Benzenemethanol,5-bromo-2-chloro- - Names and Identifiers
Benzenemethanol,5-bromo-2-chloro- - Physico-chemical Properties
Molecular Formula | C7H6BrClO
|
Molar Mass | 221.48 |
Density | 1.685 |
Melting Point | 92-96 °C (lit.) |
Boling Point | 295.8±25.0 °C(Predicted) |
Flash Point | 132.7°C |
Vapor Presure | 0.000675mmHg at 25°C |
Appearance | White to light yellow crystal powder |
Color | White to Almost white |
pKa | 13.69±0.10(Predicted) |
Storage Condition | Sealed in dry,Room Temperature |
Refractive Index | 1.605 |
MDL | MFCD02683548 |
Physical and Chemical Properties | WGK Germany:3 |
Benzenemethanol,5-bromo-2-chloro- - Risk and Safety
Benzenemethanol,5-bromo-2-chloro- - Introduction
5-bromo-2-chloroform is an organic compound with the chemical formula C7H6BrClO. The following is an introduction to its nature, use, preparation and safety information:
Nature:
-Appearance: 5-bromo-2-chorobenzyl alcohol is a colorless or slightly yellow crystal.
-Solubility: insoluble in water, soluble in organic solvents.
-Melting point: about 56-58 degrees Celsius.
Use:
-Pharmaceutical field: 5-Bromo-2-chlorobenzyl alcohol can be used in the synthesis of pharmaceutical intermediates, such as anti-epileptic drugs and anti-shock drugs.
-Pesticide field: It can also be used as a pesticide intermediate for the synthesis of some pesticides and herbicides.
-Other uses: 5-bromo-2-chloroform alcohol can also be used as catalysts and solvents in organic synthesis reactions.
Method:
5-Bromo-2-chlorobenzyl alcohol can be synthesized by the following steps:
1. Take 2-chlorobenzyl alcohol and hydrobromic acid to react to obtain 2-bromobenzyl alcohol.
2. 2-bromobenzyl alcohol is reacted with cis-β-bromo-p-chlorobenzyl alcohol, and 5-Bromo-2-chlorobenzyl alcohol is obtained by hydroxy-Grignard reduction.
Precautions and Safety Information:
-5-bromo-2-chorobenzyl alcohol is irritating to the eyes and skin, so wear appropriate personal protective equipment such as safety glasses, gloves and lab coats.
-Avoid fire and high temperature conditions during use or storage to prevent fire or explosion.
-Please follow the correct laboratory procedures when using, and keep 5-bromo-2-chorobenzyl alcohol properly.
-When disposing of waste, please dispose of it in accordance with local regulations.
Last Update:2024-04-09 02:00:42