Bifenazate
BIFENAZATE
CAS: 149877-41-8
Molecular Formula: C17H20N2O3
Bifenazate - Names and Identifiers
| Name | BIFENAZATE |
| Synonyms | D2341 NC-1111 ACRAMITE FLORAMITE MITEKOHNE BIFENAZATE BIFENAZATE STANDARD bifenazate(ansi,bsi) Bifenazate Solution, 100ppm propan-2-yl 2-(4-methoxybiphenyl-3-yl)hydrazinecarboxylate |
| CAS | 149877-41-8 |
| EINECS | 442-820-5 |
| InChI | InChI=1/C17H20N2O3/c1-12(2)22-17(20)19-18-15-11-14(9-10-16(15)21-3)13-7-5-4-6-8-13/h4-12,18H,1-3H3,(H,19,20) |
| InChIKey | VHLKTXFWDRXILV-UHFFFAOYSA-N |
Bifenazate - Physico-chemical Properties
| Molecular Formula | C17H20N2O3 |
| Molar Mass | 300.35 |
| Density | 1.31 g/cm3(Temp: 25 °C) |
| Melting Point | 122℃ |
| Appearance | neat |
| BRN | 9632665 |
| pKa | 9.84±0.43(Predicted) |
| Storage Condition | Sealed in dry,2-8°C |
| Refractive Index | 1.577 |
| Physical and Chemical Properties | Storage Conditions: 0-6 ℃ |
Bifenazate - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | R36 - Irritating to the eyes R43 - May cause sensitization by skin contact |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37 - Wear suitable protective clothing and gloves. |
| UN IDs | UN 3077 9 / PGIII |
| WGK Germany | 3 |
| Toxicity | LD50 in rats (mg/kg): 5000 orally, >2000 dermally (Dekeyser) |
Bifenazate - Reference
| Reference Show more | 1. [IF=3.585] Q.-T. Huang et al."Functional integrity of honeybee (Apis mellifera L.) resistant to dieldrin γ-aminobutyric acid receptor channels conjugated with three fluorescent proteins."Insect Mol Biol. 2019 Jun;28(3):313-320 |
Bifenazate - Reference Information
| EPA chemical information | Information provided by: ofmpub.epa.gov (external link) |
| introduction | biphenylhydrazine ester is a novel acaricide developed by Uniloyle Chemical Company (Compton Group Company) in the United States. It has a wide range of prevention and control spectrum, safety, strong knockdown, stable performance, and is not affected by light and heat. It is resistant to rain erosion, has good efficacy, and is friendly to beneficial insects and natural enemies, it can quickly reduce the base of harmful mites, kill eggs and kill mites, and more thoroughly control the harm of harmful mites. It is more sensitive to difficult-to-control harmful mites such as spider mites, and has a long duration. It can protect crops from damage for a long time. It is very suitable for integrated pest management. |
| Mechanism of Action | Biphenyl mite mainly acts on the complex III site of the cell's mitochondria and inhibits the cell's mitochondrial energy transfer. The mites began to show paralysis and excessive excitement 3-10 hours after contact with the drug, stopped eating and laying eggs within 1-2 days, and the mites gradually died within 3-4 days. |
| use | biphenylhydrazine ester is a new type of selective foliar acaricide, which is not systemic and is mainly used for the control of active spider mites, but it has a killing effect on other mites, especially spider mites. It has good control effect on citrus red spider, rust tick, yellow spider, short beard mite, hawthorn spider mite, cinnabar spider mite and two spot spider mite and other agricultural harmful mites. |
| toxicity | the original drug of bifylhydrazine has an acute oral and percutaneous LD50 of rats> 5000mg/kg, and acute inhalation of LC50>/L; No irritation to rabbit eyes and skin: guinea pig skin sensitization test results showed no sensitization. Results of 90-day subchronic feeding test in rats: the maximum non-effective dose was/kg d for male rats. Female rats were/kg · d;4 mutagenic tests: Ames test, micronucleus test, in vitro mammalian gene mutation test, in vitro mammalian chromosome aberration test were all negative, and no mutagenic effect was found. Bifylhydrazine 480g/L SC on rats with acute transdermal LD50>5000mg/kg, acute transdermal LD50>2000mg/kg, acute inhalation of 2LLC ∞>2mg/L; no irritation to rabbit skin, rabbit eyes irritation, but no corrosive effect: guinea pig skin without sensitization. |
| biological activity | Bifenazate is a carbolazine acaricide with a concentration of 25 ppm, which can 100% control mites. Bifenazate are positive allosteric modulators of GABA receptors. |
| target | GABA receptor. |
| toxic substance data | information provided by: pubchem.ncbi.nlm.nih.gov (external link) |
Last Update：2024-04-10 22:29:15
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View History
Bifenazate
P-TOLYL SALICYLATE
Benzenamine, 4-fluoro-2-methoxy-5-nitro-
Trimethyl(4-pyridyl)tin
奥沙拉嗪杂质B (EP)
Albumin (chicleen egg)
1-[4-(METHYLSULFONYL)PHENYL]PIPERAZINE
甲基丙烯酸磷酸酯
BIS(TRIMETHYLSILYL)ACETYLENE
N-(氯乙酰基)糖胶
P-TOLYL SALICYLATE
Benzenamine, 4-fluoro-2-methoxy-5-nitro-
Trimethyl(4-pyridyl)tin
奥沙拉嗪杂质B (EP)
Albumin (chicleen egg)
1-[4-(METHYLSULFONYL)PHENYL]PIPERAZINE
甲基丙烯酸磷酸酯
BIS(TRIMETHYLSILYL)ACETYLENE
N-(氯乙酰基)糖胶