Biotin-PEG2-COOH

Name	Biotin-PEG2-Acid
Synonyms	Biotin-PEG2-COOH BIOTIN-PEG2-ACID Biotin-PEG2-Acid (+)-Biotin-PEG2-acid (+)-Biotin-PEG2-CH2CH2COOH Propanoic acid, 3-[2-[2-[[5-[(3aR,4R,6aS)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-1-oxopentyl]amino]ethoxy]ethoxy]-, rel-
CAS	1365655-89-5

Molecular Formula	C17H29N3O6S
Molar Mass	403.49
Density	1.234±0.06 g/cm3(Predicted)
Boling Point	752.2±60.0 °C(Predicted)
pKa	4.28±0.10(Predicted)
Storage Condition	Room Temprature
In vitro study	ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

bioactivity	Biotin-PEG2-acid is a non-degradable ADC linker containing 2 units of PEG, it can be used to synthesize antibody-conjugated drugs (ADCS). Biotin-PEG2-acid is a PROTAC linker, belonging to the PEG class, which can be used to synthesize PROTAC molecules.
Target	PEGs Non-cleavable
in vitro study	ADCs are combined of an antibody to which is attached an ADC cytoxin through an ADC linker. PROTACs contains two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intrinsic ubiquitin-proteasome system to selective grade target proteins.

Last Update：2024-04-09 21:11:58

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Biotin-PEG2-COOH

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