Bis((4S)-4,5-dihydro-4-phenyloxazol-2-yl)methane
(S,S)-2,2'-methylenebis(4-phenyl-2-oxazoline)
CAS: 132098-59-0
Molecular Formula: C19H18N2O2
Bis((4S)-4,5-dihydro-4-phenyloxazol-2-yl)methane - Names and Identifiers
| Name | (S,S)-2,2'-methylenebis(4-phenyl-2-oxazoline) |
| Synonyms | 2,2'-METHYLENEBIS[(4S)-4-PHENYL-2-OXAZOLINE] (S,S)-2,2'-methylenebis(4-phenyl-2-oxazoline) (S,S)-2,2'-METHYLENEBIS(4-PHENYL-2-OXAZOLINE) 4(S,S)-2,2'-METHYLENEBIS(4-PHENYL-2-OXAZOLINE) Bis((S)-4-phenyl-4,5-dihydrooxazol-2-yl)methane Bis((4S)-4,5-dihydro-4-phenyloxazol-2-yl)methane 2,2'-Methylenebis[(4S)-4-phenyl-4,5-dihydro-2-oxazole] 2,2′-Methylenebis[(4S)-4-phenyl-2-oxazoline],(S,S)-2,2′-Methylenebis(4-phenyl-2-oxazoline) |
| CAS | 132098-59-0 |
| InChI | InChI=1/C19H18N2O2/c1-3-7-14(8-4-1)16-12-22-18(20-16)11-19-21-17(13-23-19)15-9-5-2-6-10-15/h1-10,16-17H,11-13H2/t16-,17-/m0/s1 |
Bis((4S)-4,5-dihydro-4-phenyloxazol-2-yl)methane - Physico-chemical Properties
| Molecular Formula | C19H18N2O2 |
| Molar Mass | 306.36 |
| Density | 1.28g/mLat 25°C(lit.) |
| Boling Point | 131-134°C0.01mm Hg(lit.) |
| Flash Point | >230°F |
| Vapor Presure | 3.6E-08mmHg at 25°C |
| BRN | 4202633 |
| pKa | 4.54±0.70(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
| Refractive Index | n20/D 1.587 |
Bis((4S)-4,5-dihydro-4-phenyloxazol-2-yl)methane - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
| WGK Germany | 3 |
Bis((4S)-4,5-dihydro-4-phenyloxazol-2-yl)methane - Introduction
2,2 '-Methylenebis [(4,S)-4-phenyl-2-oxazoline] is an organic compound with the chemical formula C24H20N2O2 and a molecular weight of 372.43G/mole.
The compound is commonly used as a stereoselective catalyst in organic synthesis reactions, and has good catalytic activity and selectivity. It is usually used as a chiral ligand to participate in metal-catalyzed reactions, such as asymmetric nucleophilic substitution reactions, cyclization reactions and oxidation reactions.
The preparation method of 2,2 '-methylenebis [(4,S)-4-phenyl-2-oxazoline] is generally obtained by chemical synthesis. The specific method includes reacting 4-phenyl-2-oxazoline with an appropriate ligand and further reacting with a metal salt to obtain the target compound.
Regarding safety information, this compound has not been subjected to detailed toxicity studies, so caution is required when using it. Regular laboratory safety practices should be followed to avoid contact with skin, eyes and inhalation of dust. At the same time, if an accident occurs, immediately flush the affected area with plenty of water and seek medical help.
It should be emphasized that the above information is for reference only. Please check and read the relevant chemical literature reliably before actual operation, and comply with laboratory and safety regulations.
The compound is commonly used as a stereoselective catalyst in organic synthesis reactions, and has good catalytic activity and selectivity. It is usually used as a chiral ligand to participate in metal-catalyzed reactions, such as asymmetric nucleophilic substitution reactions, cyclization reactions and oxidation reactions.
The preparation method of 2,2 '-methylenebis [(4,S)-4-phenyl-2-oxazoline] is generally obtained by chemical synthesis. The specific method includes reacting 4-phenyl-2-oxazoline with an appropriate ligand and further reacting with a metal salt to obtain the target compound.
Regarding safety information, this compound has not been subjected to detailed toxicity studies, so caution is required when using it. Regular laboratory safety practices should be followed to avoid contact with skin, eyes and inhalation of dust. At the same time, if an accident occurs, immediately flush the affected area with plenty of water and seek medical help.
It should be emphasized that the above information is for reference only. Please check and read the relevant chemical literature reliably before actual operation, and comply with laboratory and safety regulations.
Last Update：2024-04-10 22:29:15
