Bis-CME
BIS(CHLOROMETHYL)ETHER
CAS: 542-88-1
Molecular Formula: C2H4Cl2O
Bis-CME - Names and Identifiers
| Name | BIS(CHLOROMETHYL)ETHER |
| Synonyms | BCME Bis-CME bis-chloromethyl bis(chloromethyl) BIS(CHLOROMETHYL)ETHER chloro(chloromethoxy)methane Chloro(chloromethoxy) methane alpha,alpha’-dichlorodimethylether alpha,alpha'-Dichlorodimethyl ether |
| CAS | 542-88-1 |
| EINECS | 208-832-8 |
Bis-CME - Physico-chemical Properties
| Molecular Formula | C2H4Cl2O |
| Molar Mass | 114.96 |
| Density | 1.267 |
| Melting Point | 171℃ |
| Boling Point | 106℃ |
| Flash Point | 75℃ |
| Solubility | Soluble in alcohol, ether (Weast, 1986), benzene (Hawley, 1981), and other solvents includingacetone and chloroform. |
| Vapor Presure | 30 at 22 °C (Dreisbach, 1952) |
| Appearance | Colorless liquid |
| Color | Colorless liquid with a suffocating odor |
| Exposure Limit | TLV-TWA 0.0047 mg (0.001 ppm)/m3 (Hu man Carcinogen) (ACGIH); Human and Animal Carcinogen-Sufficient Evidence (IARC);Carcinogen (OSHA). |
| Storage Condition | -20°C Freezer |
| Refractive Index | 1.44433 |
| Physical and Chemical Properties | Colorless liquid. Melting point -41.5 ℃, boiling point 104-105 ℃, relative density 1.315(20/4 ℃), refractive index 1.4346. Can be miscible with ethanol and ether. Decompose into hydrogen chloride and formaldehyde in water. |
Bis-CME - Risk and Safety
| Hazard Symbols | T+ - Very toxic |
| Risk Codes | R10 - Flammable R36/37/38 - Irritating to eyes, respiratory system and skin. R40 - Limited evidence of a carcinogenic effect R26 - Very Toxic by inhalation R24 - Toxic in contact with skin R22 - Harmful if swallowed R45 - May cause cancer |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S53 - Avoid exposure - obtain special instructions before use. |
| UN IDs | 2249 |
| Hazard Class | 6.1(a) |
| Packing Group | I |
| Toxicity | Acute oral LD50 for rats is 210 mg/kg (quoted, RTECS, 1985). |
Bis-CME - References
| (IARC) carcinogen classification | 1 (Vol. 4, Sup 7, 100F) 2012 |
| EPA chemical substance information | information provided by: ofmpeb.epa.gov (external link) |
| purpose | for drug Xiaoliu, eight nitrogen dipropyl ether, phosphorus intermediates. It is also an intermediate of vitamin B2 (a raw material for the synthesis of 3, 4-dimethylaniline). |
| production method | is obtained from the chlorination of paraformaldehyde. |
| category | toxic substances |
| toxicity grade | high toxicity |
| Acute toxicity | oral-rat LD50:210 mg/kg; Inhalation-mouse LC50: 0.025g/m3/6 h |
| explosive hazard characteristics | explosive when mixed with air; Long-standing generation of explosive peroxide |
| flammability hazard characteristics | flammable; Heat, water decomposition of toxic hydrogen chloride gas |
| storage and transportation characteristics | The warehouse is ventilated and dried at low temperature; Separate from oxidant and food |
| extinguishing agent | water, carbon dioxide, dry powder |
| Occupational Standard | TWA 0.0047 mg/m3; Tel 0.015 mg/m3 |
| toxic substance data | information provided by: pubchem.ncbi.nlm.nih.gov (external link) |
Last Update：2024-04-10 22:29:15
