Bistrimethylsilylchloromethane
Bis(trimethylsilyl)methyl chloride
CAS: 5926-35-2
Molecular Formula: C7H19ClSi2
Bistrimethylsilylchloromethane - Names and Identifiers
| Name | Bis(trimethylsilyl)methyl chloride |
| Synonyms | Bistrimethylsilylchloromethane BIS(TRIMETHYLSILYL)CHLOROMETHANE Chloro-bis(trimethylsilyl)methane Bis(trimethylsilyl)methyl chloride BIS(TRIMETHYLSILYL)METHYL CHLORIDE Chloro-bis-trimethylsilanyl-methane (Chloromethylene)bis(trimethylsilane) (chloromethanediyl)bis(trimethylsilane) chloro(trimethylsilyl)methyl]-trimethylsilane Silane, 1,1'-(chloromethylene)bis[1,1,1-trimethyl- N-[(2-hydroxynaphthalen-1-yl)(4-nitrophenyl)methyl]acetamide |
| CAS | 5926-35-2 |
| InChI | InChI=1/C19H16N2O4/c1-12(22)20-19(14-6-9-15(10-7-14)21(24)25)18-16-5-3-2-4-13(16)8-11-17(18)23/h2-11,19,23H,1H3,(H,20,22) |
Bistrimethylsilylchloromethane - Physico-chemical Properties
| Molecular Formula | C7H19ClSi2 |
| Molar Mass | 194.85 |
| Density | 0.892 g/mL at 25 °C (lit.) |
| Boling Point | 57-60 °C/15 mmHg (lit.) |
| Flash Point | 120°F |
| Solubility | soluble in common organic solvents (DMF, THF,Et2O, CH2Cl2). |
| Vapor Presure | 1.99E-17mmHg at 25°C |
| Specific Gravity | 0.892 |
| BRN | 1736681 |
| Sensitive | 4: no reaction with water under neutral conditions |
| Refractive Index | n20/D 1.449(lit.) |
Bistrimethylsilylchloromethane - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | R10 - Flammable R36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
| UN IDs | UN 1993 3/PG 3 |
| WGK Germany | 3 |
| FLUKA BRAND F CODES | 21 |
| TSCA | No |
| Hazard Class | 3.2 |
| Packing Group | III |
Bistrimethylsilylchloromethane - Introduction
Bis(trimethylsilyl)methyl chloride(Bis(trimethylsilyl)methyl chloride) is an organic compound with the chemical formula C4H13ClSi2. Here are some information about its properties, uses, formulation and safety:
Nature:
-Appearance: Bis(trimethylsilyl)methyl chloride is a colorless liquid.
-Solubility: It is soluble in organic solvents such as ether and dimethylformamide.
-Melting point and boiling point: melting point is -80°C, boiling point is 95-97°C.
-Density: Its density is about 0.907g/cm3.
-stability: Bis(trimethylsilyl)methyl chloride is relatively stable at room temperature, but it is decomposed by heat, so it is necessary to avoid long-term high temperature exposure.
Use:
- Bis(trimethylsilyl)methyl chloride are commonly used as intermediates in organic synthetic chemicals. It can be used to synthesize organic compounds with important application value, such as bioactive compounds or drugs.
-It can also be used as a silicone reagent, involved in the synthesis and modification of polymers, coatings and electronic materials.
Preparation Method:
- Bis(trimethylsilyl)methyl chloride can be prepared by reacting trimethylsilyl methanol with chloroform. In the reaction, trimethylsilyl methanol and trichloromethane are esterified under the action of acid catalyst to generate the target product. After the reaction, it is also necessary to obtain a pure product by a purification step.
Safety Information:
- Bis(trimethylsilyl)methyl chloride is an organic compound and needs to be handled with caution. Wear appropriate personal protective equipment such as protective gloves, goggles, and lab coats during operation.
-Avoid contact with skin, eyes and clothing, and avoid inhaling vapors.
-When handling the compound in the laboratory, the relevant laboratory safety operating regulations and guidelines should be followed.
-In case of abnormal conditions, such as leakage or discomfort, the operation should be stopped immediately and appropriate measures should be taken, such as ventilation, cleaning and emergency treatment.
the above is a basic introduction to the Bis(trimethylsilyl)methyl chloride for reference. Before laboratory operation or application, it is recommended to consult the relevant literature and professionals.
Nature:
-Appearance: Bis(trimethylsilyl)methyl chloride is a colorless liquid.
-Solubility: It is soluble in organic solvents such as ether and dimethylformamide.
-Melting point and boiling point: melting point is -80°C, boiling point is 95-97°C.
-Density: Its density is about 0.907g/cm3.
-stability: Bis(trimethylsilyl)methyl chloride is relatively stable at room temperature, but it is decomposed by heat, so it is necessary to avoid long-term high temperature exposure.
Use:
- Bis(trimethylsilyl)methyl chloride are commonly used as intermediates in organic synthetic chemicals. It can be used to synthesize organic compounds with important application value, such as bioactive compounds or drugs.
-It can also be used as a silicone reagent, involved in the synthesis and modification of polymers, coatings and electronic materials.
Preparation Method:
- Bis(trimethylsilyl)methyl chloride can be prepared by reacting trimethylsilyl methanol with chloroform. In the reaction, trimethylsilyl methanol and trichloromethane are esterified under the action of acid catalyst to generate the target product. After the reaction, it is also necessary to obtain a pure product by a purification step.
Safety Information:
- Bis(trimethylsilyl)methyl chloride is an organic compound and needs to be handled with caution. Wear appropriate personal protective equipment such as protective gloves, goggles, and lab coats during operation.
-Avoid contact with skin, eyes and clothing, and avoid inhaling vapors.
-When handling the compound in the laboratory, the relevant laboratory safety operating regulations and guidelines should be followed.
-In case of abnormal conditions, such as leakage or discomfort, the operation should be stopped immediately and appropriate measures should be taken, such as ventilation, cleaning and emergency treatment.
the above is a basic introduction to the Bis(trimethylsilyl)methyl chloride for reference. Before laboratory operation or application, it is recommended to consult the relevant literature and professionals.
Last Update：2024-04-09 15:17:58
