Boc-(2S,3RS)-2-amino-3-hydroxy-4-methylpentanoicacid
Boc-(2S,3RS)-2-amino-3-hydroxy-4-methylpentanoicacid
CAS: 1217531-78-6
Molecular Formula: C11H21NO5
Boc-(2S,3RS)-2-amino-3-hydroxy-4-methylpentanoicacid - Names and Identifiers
Boc-(2S,3RS)-2-amino-3-hydroxy-4-methylpentanoicacid - Physico-chemical Properties
| Molecular Formula | C11H21NO5 |
| Molar Mass | 247.29 |
| Storage Condition | Room Temprature |
| Sensitive | Irritant |
| MDL | MFCD02682586 |
Boc-(2S,3RS)-2-amino-3-hydroxy-4-methylpentanoicacid - Risk and Safety
| Hazard Class | IRRITANT |
Boc-(2S,3RS)-2-amino-3-hydroxy-4-methylpentanoicacid - Introduction
The Boc-(2S,3RS)-acid, also known as Boc-(2S,3RS)-α-amino-β-hydroxy-γ-methylpentanoic acid, is an organic compound.
This compound has the following properties:
-Molecular formula: C13H25NO5
-Molecular weight: 279.34g/mol
-Appearance: Colorless to white crystalline powder
-Melting Point: 72-75°C
-Solubility: It can be dissolved in some organic solvents, such as ethanol, dimethylformamide and dichloromethane.
One of the main uses of Boc-(2S,3RS)-acid is as an amino protective agent in synthesis. It may protect the amino function by a Boc protecting group to prevent unwanted side reactions in the reaction. In addition, it can also be used as an intermediate for the synthesis of polypeptides.
One way to prepare Boc-(2S,3RS)-acid is to react an appropriate amount of L-leucine and (S)-or (R)-3-hydroxy-4-methylpentanoic acid under acid catalysis under appropriate conditions. The resulting reactant is then reacted with Boc-anhydride to obtain the target product.
Regarding safety information, Boc-(2S,3RS)-Acid is not particularly dangerous. However, as any chemical substance, it should still comply with laboratory safety requirements, such as wearing appropriate personal protective equipment and avoiding contact with skin, eyes and inhalation. If necessary, maintain good ventilation during operation.
This compound has the following properties:
-Molecular formula: C13H25NO5
-Molecular weight: 279.34g/mol
-Appearance: Colorless to white crystalline powder
-Melting Point: 72-75°C
-Solubility: It can be dissolved in some organic solvents, such as ethanol, dimethylformamide and dichloromethane.
One of the main uses of Boc-(2S,3RS)-acid is as an amino protective agent in synthesis. It may protect the amino function by a Boc protecting group to prevent unwanted side reactions in the reaction. In addition, it can also be used as an intermediate for the synthesis of polypeptides.
One way to prepare Boc-(2S,3RS)-acid is to react an appropriate amount of L-leucine and (S)-or (R)-3-hydroxy-4-methylpentanoic acid under acid catalysis under appropriate conditions. The resulting reactant is then reacted with Boc-anhydride to obtain the target product.
Regarding safety information, Boc-(2S,3RS)-Acid is not particularly dangerous. However, as any chemical substance, it should still comply with laboratory safety requirements, such as wearing appropriate personal protective equipment and avoiding contact with skin, eyes and inhalation. If necessary, maintain good ventilation during operation.
Last Update：2024-04-10 22:29:15
