Boc-(S)-3-Thienylglycine
Boc-(S)-3-Thienylglycine
CAS: 910309-12-5
Molecular Formula: C11H15NO4S
Boc-(S)-3-Thienylglycine - Names and Identifiers
Boc-(S)-3-Thienylglycine - Physico-chemical Properties
| Molecular Formula | C11H15NO4S |
| Molar Mass | 257.31 |
| Density | 1.273 |
| Storage Condition | 2-8°C |
Boc-(S)-3-Thienylglycine - Risk and Safety
| WGK Germany | 3 |
| Hazard Class | IRRITANT |
Boc-(S)-3-Thienylglycine - Introduction
Boc-(S)-3-Thienylglycine is an organic compound with the chemical formula C11H15NO4S. The following is an introduction to its nature, use, preparation and safety information:
Nature:
-Appearance: White to off-white solid
-Melting point: about 70-75 ℃
-Solubility: Soluble in some organic solvents, such as dimethylformamide (DMF) and dichloromethane
Use:
- Boc-(S)-3-Thienylglycine is commonly used as an intermediate in chiral synthesis.
-It can be used for the synthesis of chiral drugs, peptides and other organic molecules.
Preparation Method:
There are many methods for the preparation of-Boc-(S)-3-Thienylglycine, one of which is a simple method:
1. 3-Thiophenylglycine (3-thiophenylglycine) is reacted with p-iodotoluene (p-iodotoluene) to give 3-(4-iodomethylphenyl)-thiophenylglycine.
2. The product is then subjected to a protection reaction, and the amino group is protected using an amino protecting agent Boc(tert-butyloxycarbonyl).
Safety Information:
The safety profile of-Boc-(S)-3-Thienylglycine is similar to that of general organic compounds.
-During the operation, normal laboratory practices should be followed, such as wearing appropriate protective equipment and avoiding exposure to skin and eyes.
Nature:
-Appearance: White to off-white solid
-Melting point: about 70-75 ℃
-Solubility: Soluble in some organic solvents, such as dimethylformamide (DMF) and dichloromethane
Use:
- Boc-(S)-3-Thienylglycine is commonly used as an intermediate in chiral synthesis.
-It can be used for the synthesis of chiral drugs, peptides and other organic molecules.
Preparation Method:
There are many methods for the preparation of-Boc-(S)-3-Thienylglycine, one of which is a simple method:
1. 3-Thiophenylglycine (3-thiophenylglycine) is reacted with p-iodotoluene (p-iodotoluene) to give 3-(4-iodomethylphenyl)-thiophenylglycine.
2. The product is then subjected to a protection reaction, and the amino group is protected using an amino protecting agent Boc(tert-butyloxycarbonyl).
Safety Information:
The safety profile of-Boc-(S)-3-Thienylglycine is similar to that of general organic compounds.
-During the operation, normal laboratory practices should be followed, such as wearing appropriate protective equipment and avoiding exposure to skin and eyes.
Last Update：2024-04-09 02:00:49
