Boc-3-(Fmoc-amino)-L-alanine, Nα-Boc-Nβ-Fmoc-L-2,3-diaminopropionic acid
Boc-Dap(Fmoc)-OH
CAS: 122235-70-5
Molecular Formula: C23H26N2O6
Boc-3-(Fmoc-amino)-L-alanine, Nα-Boc-Nβ-Fmoc-L-2,3-diaminopropionic acid - Names and Identifiers
| Name | Boc-Dap(Fmoc)-OH |
| Synonyms | Boc-Dap(Fmoc)-OH BOC-DAP(FMOC)-OH Boc-Dpr(Fmoc)-OH Boc-Dapa(FMoc)-OH Boc-L-2,3-Diaminopropionic acid(Fmoc) N-Boc-N-Fmoc-(S)-2,3-diaminopropionic acid N-α-Boc-N-β-Fmoc-L-2,3-diamiopropionic acid N-.ALPHA.-BOC-N-.BETA.-FMOC-L-2,3-DIAMIOPROPIONIC ACID (S)-2,3-Diaminopropanoic acid, N2-BOC, N3-FMOC protected 3-[(9H-Fluoren-9-ylmethoxycarbonyl)amino]-L-alanine, N-BOC protected Boc-3-(Fmoc-amino)-L-alanine, Nα-Boc-Nβ-Fmoc-L-2,3-diaminopropionic acid NALPHA-tert-Butoxycarbonyl-NB-9-fluorenylmethoxycarbonyl-L-2,3-diaminopropi 3-[(tert-butoxycarbonyl)amino]-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanine N-(tert-butoxycarbonyl)-3-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-L-alanine |
| CAS | 122235-70-5 |
| EINECS | 1533716-785-6 |
| InChI | InChI=1/C23H26N2O6/c1-23(2,3)31-22(29)25-19(20(26)27)12-24-21(28)30-13-18-16-10-6-4-8-14(16)15-9-5-7-11-17(15)18/h4-11,18-19H,12-13H2,1-3H3,(H,24,28)(H,25,29)(H,26,27)/t19-/m0/s1 |
Boc-3-(Fmoc-amino)-L-alanine, Nα-Boc-Nβ-Fmoc-L-2,3-diaminopropionic acid - Physico-chemical Properties
| Molecular Formula | C23H26N2O6 |
| Molar Mass | 426.46 |
| Density | 1.263±0.06 g/cm3(Predicted) |
| Boling Point | 652.5±55.0 °C(Predicted) |
| Flash Point | 348.4°C |
| Solubility | Soluble in 2ml dimethyl formamide 0.3gram. |
| Vapor Presure | 6.45E-18mmHg at 25°C |
| BRN | 4771385 |
| pKa | 3?+-.0.10(Predicted) |
| Storage Condition | Sealed in dry,2-8°C |
| Refractive Index | 1.58 |
Boc-3-(Fmoc-amino)-L-alanine, Nα-Boc-Nβ-Fmoc-L-2,3-diaminopropionic acid - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| WGK Germany | 3 |
| HS Code | 29242990 |
| Hazard Class | IRRITANT |
Boc-3-(Fmoc-amino)-L-alanine, Nα-Boc-Nβ-Fmoc-L-2,3-diaminopropionic acid - Introduction
Tert-butoxycarbonyl-DAP, full name tert-butoxycarbonyl-N,N'-diaminopyloxyacetic acid, is an amino acid containing a tert-butoxycarbonyl (t-BOC) protecting group. The following is a description of the properties, uses, preparation and safety information of tert-butoxycarbonyl-DAP:
Nature:
-Appearance: White crystalline solid
-Molecular formula: C13H24N2O5
-Molecular weight: 292.34g/mol
-melting point: 85-88 ℃
-Solubility: Soluble in organic solvents such as dimethyl sulfoxide and dichloromethane, slightly soluble in ethanol and acetonitrile.
Use:
-tert-Butoxycarbonyl-DAP is a commonly used amino acid protecting group. By adding it to the amino group of the amino acid, it can protect the amino acid from the interference of other chemical reactants in the environment, so as to maintain its stability.
-tert-Butoxycarbonyl-DAP is widely used in peptide synthesis and solid phase synthesis. By adding t-butoxycarbonyl-DAP to the end of the synthetic peptide, the amino group of the peptide chain can be protected to prevent non-specific reactions during the synthesis.
Preparation Method:
-tert-Butoxycarbonyl-DAP is usually prepared by reacting DAP(N,N'-diaminoalanine) with tert-butoxycarbonyl anhydride.
Safety Information:
-tert-Butoxycarbonyl-DAP is a chemical and should be handled in accordance with the relevant safety procedures.
-It may cause irritation and sensitivity reactions to the eyes, skin, and respiratory tract, so appropriate personal protective measures should be taken during operation, such as wearing gloves, goggles and masks.
-When storing, store tert-butoxycarbonyl-DAP in a dry, cool place and avoid contact with oxidizing agents.
-If you inhale, come into contact with, or ingest tert-butoxycarbonyl-DAP, seek medical attention immediately and go to a medical institution with a label.
Nature:
-Appearance: White crystalline solid
-Molecular formula: C13H24N2O5
-Molecular weight: 292.34g/mol
-melting point: 85-88 ℃
-Solubility: Soluble in organic solvents such as dimethyl sulfoxide and dichloromethane, slightly soluble in ethanol and acetonitrile.
Use:
-tert-Butoxycarbonyl-DAP is a commonly used amino acid protecting group. By adding it to the amino group of the amino acid, it can protect the amino acid from the interference of other chemical reactants in the environment, so as to maintain its stability.
-tert-Butoxycarbonyl-DAP is widely used in peptide synthesis and solid phase synthesis. By adding t-butoxycarbonyl-DAP to the end of the synthetic peptide, the amino group of the peptide chain can be protected to prevent non-specific reactions during the synthesis.
Preparation Method:
-tert-Butoxycarbonyl-DAP is usually prepared by reacting DAP(N,N'-diaminoalanine) with tert-butoxycarbonyl anhydride.
Safety Information:
-tert-Butoxycarbonyl-DAP is a chemical and should be handled in accordance with the relevant safety procedures.
-It may cause irritation and sensitivity reactions to the eyes, skin, and respiratory tract, so appropriate personal protective measures should be taken during operation, such as wearing gloves, goggles and masks.
-When storing, store tert-butoxycarbonyl-DAP in a dry, cool place and avoid contact with oxidizing agents.
-If you inhale, come into contact with, or ingest tert-butoxycarbonyl-DAP, seek medical attention immediately and go to a medical institution with a label.
Last Update：2024-04-10 22:29:15
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CAS: 122235-70-5
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QQ: 3008007409
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CAS: 122235-70-5
Tel: 18301782025
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Mobile: 18021002903
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