Boc-Dpr(Fmoc)-OH

Boc-Dpr(Fmoc)-OH - Names and Identifiers

Name	Boc-Dap(Fmoc)-OH
Synonyms	Boc-Dap(Fmoc)-OH BOC-DAP(FMOC)-OH Boc-Dpr(Fmoc)-OH Boc-Dapa(FMoc)-OH Boc-L-2,3-Diaminopropionic acid(Fmoc) N-Boc-N-Fmoc-(S)-2,3-diaminopropionic acid N-α-Boc-N-β-Fmoc-L-2,3-diamiopropionic acid N-.ALPHA.-BOC-N-.BETA.-FMOC-L-2,3-DIAMIOPROPIONIC ACID (S)-2,3-Diaminopropanoic acid, N2-BOC, N3-FMOC protected 3-[(9H-Fluoren-9-ylmethoxycarbonyl)amino]-L-alanine, N-BOC protected Boc-3-(Fmoc-amino)-L-alanine, Nα-Boc-Nβ-Fmoc-L-2,3-diaminopropionic acid NALPHA-tert-Butoxycarbonyl-NB-9-fluorenylmethoxycarbonyl-L-2,3-diaminopropi 3-[(tert-butoxycarbonyl)amino]-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanine N-(tert-butoxycarbonyl)-3-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-L-alanine
CAS	122235-70-5
EINECS	1533716-785-6
InChI	InChI=1/C23H26N2O6/c1-23(2,3)31-22(29)25-19(20(26)27)12-24-21(28)30-13-18-16-10-6-4-8-14(16)15-9-5-7-11-17(15)18/h4-11,18-19H,12-13H2,1-3H3,(H,24,28)(H,25,29)(H,26,27)/t19-/m0/s1

Boc-Dpr(Fmoc)-OH - Physico-chemical Properties

Molecular Formula	C23H26N2O6
Molar Mass	426.46
Density	1.263±0.06 g/cm3(Predicted)
Boling Point	652.5±55.0 °C(Predicted)
Flash Point	348.4°C
Solubility	Soluble in 2ml dimethyl formamide 0.3gram.
Vapor Presure	6.45E-18mmHg at 25°C
BRN	4771385
pKa	3?+-.0.10(Predicted)
Storage Condition	Sealed in dry,2-8°C
Refractive Index	1.58

Boc-Dpr(Fmoc)-OH - Risk and Safety

Hazard Symbols	Xi - Irritant
WGK Germany	3
HS Code	29242990
Hazard Class	IRRITANT

Boc-Dpr(Fmoc)-OH - Introduction

Tert-butoxycarbonyl-DAP, full name tert-butoxycarbonyl-N,N'-diaminopyloxyacetic acid, is an amino acid containing a tert-butoxycarbonyl (t-BOC) protecting group. The following is a description of the properties, uses, preparation and safety information of tert-butoxycarbonyl-DAP:

Nature:
-Appearance: White crystalline solid
-Molecular formula: C13H24N2O5
-Molecular weight: 292.34g/mol
-melting point: 85-88 ℃
-Solubility: Soluble in organic solvents such as dimethyl sulfoxide and dichloromethane, slightly soluble in ethanol and acetonitrile.

Use:
-tert-Butoxycarbonyl-DAP is a commonly used amino acid protecting group. By adding it to the amino group of the amino acid, it can protect the amino acid from the interference of other chemical reactants in the environment, so as to maintain its stability.
-tert-Butoxycarbonyl-DAP is widely used in peptide synthesis and solid phase synthesis. By adding t-butoxycarbonyl-DAP to the end of the synthetic peptide, the amino group of the peptide chain can be protected to prevent non-specific reactions during the synthesis.

Preparation Method:
-tert-Butoxycarbonyl-DAP is usually prepared by reacting DAP(N,N'-diaminoalanine) with tert-butoxycarbonyl anhydride.

Safety Information:
-tert-Butoxycarbonyl-DAP is a chemical and should be handled in accordance with the relevant safety procedures.
-It may cause irritation and sensitivity reactions to the eyes, skin, and respiratory tract, so appropriate personal protective measures should be taken during operation, such as wearing gloves, goggles and masks.
-When storing, store tert-butoxycarbonyl-DAP in a dry, cool place and avoid contact with oxidizing agents.
-If you inhale, come into contact with, or ingest tert-butoxycarbonyl-DAP, seek medical attention immediately and go to a medical institution with a label.

Last Update：2024-04-10 22:29:15