Boc-3-(Pentafluorophenyl)-L-alanine

Boc-3-(Pentafluorophenyl)-L-alanine - Names and Identifiers

Name	Boc-pentafluoro-Phe-OH
Synonyms	Boc-pentafluoro-Phe-OH Boc-Pentafluoro-L-Phe-OH Boc-L-Pentafluoro-phe-OH Boc-L-Pentafluorophenylalanine BOC-L-PENTAFLUOROPHENYLALANINE Boc-pentafluoro-L-phenylalanine Boc-3-(Pentafluorophenyl)-L-alanine L-PENTAFLUOROPHENYLALANINE, BOC PROTECTED (S)-Boc-2-amino-3-(pentafluorophenyl)propionic acid N-ALPHA-T-BUTYLOXYCARBONYL-L-PENTAFLUOROPHENYLALANINE (2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-(2,3,4,5,6-pentafluorophenyl)propanoic acid
CAS	34702-60-8

Boc-3-(Pentafluorophenyl)-L-alanine - Physico-chemical Properties

Molecular Formula	C14H14F5NO4
Molar Mass	355.26
Density	1.422±0.06 g/cm3(Predicted)
Boling Point	411.1±45.0 °C(Predicted)
pKa	3.70±0.20(Predicted)
Storage Condition	Sealed in dry,2-8°C

Boc-3-(Pentafluorophenyl)-L-alanine - Risk and Safety

Hazard Symbols	Xi - Irritant
WGK Germany	3
Hazard Note	Harmful/Irritant/Keep Cold

Boc-3-(Pentafluorophenyl)-L-alanine - Introduction

Boc-pentafluoro-Phe-OH(Boc-pentafluoro-Phe-OH) is an organic compound whose structure contains three parts: amino acid, pentafluorophenyl propyl and tert-butoxycarbonyl.

Nature:
1. appearance: generally white crystalline solid.
2. molecular formula: C14H15F5NO4.
3. Molecular weight: 371.27g/mol.
4. Melting point: about 123-125 ℃.
5. Solubility: Can be dissolved in organic solvents (such as dimethylformamide, dichloromethane, etc.) and water.

Use:
Boc-pentafluoro-Phe-OH is mainly used for protecting group chemical reaction in organic synthesis. Its tert-butoxycarbonyl group (Boc) can temporarily protect the amino group during the synthesis to prevent unnecessary reactions. In addition, it can be used in pharmaceutical synthesis, advanced organic synthesis and as a reagent for laboratory research.

Preparation Method:
A commonly used synthesis method is to react pentafluorophenyl propanol with tert-butoxycarbonyl-L-phenylalanine, and obtain Boc-pentafluoro-Phe-OH by condensation and esterification.

Safety Information:
1. Boc-pentafluoro-Phe-OH there is no obvious toxicity under normal operating conditions, it is still necessary to avoid inhalation, contact with skin and intake.
2. Wear appropriate protective gloves, glasses and overalls when operating.
3. in storage and handling to avoid contact with oxidants, strong acids and other substances, so as not to cause danger.
4. In case of accidental contact or inhalation, seek medical help immediately.
5. When disposing of waste, follow local regulations.

Last Update：2024-04-09 19:05:49