Boc-3-Fluoro-L-phenylalanine

Boc-3-Fluoro-L-phenylalanine - Names and Identifiers

Name	BOC-L-3-FLUOROPHENYLALANINE
Synonyms	Boc-Phe(3-F)-OH RARECHEM BK PT 0026 BOC-L-3-FLUOROPHENYLALANINE Boc-3-Fluoro-L-phenylalanine (S)-N-BOC-3-FLUOROPHENYLALANINE L-3-FLUOROPHENYLALANINE, BOC PROTECTED N-TERT-BUTOXYCARBONYL-3-FLUOROPHENYL-L-ALANINE N-(tert-butoxycarbonyl)-3-fluoro-D-phenylalanine N-(tert-butoxycarbonyl)-3-fluoro-L-phenylalanine N-ALPHA-T-BUTOXYCARBONYL-3-FLUORO-L-PHENYLALANINE N-ALPHA-T-BUTYLOXYCARBONYL-L-3-FLUOROPHENYLALANINE N-ALPHA-TERT-BUTYLOXYCARBONYL-3-FLUORO-L-PHENYLALANINE (2S)-2-[(tert-butoxycarbonyl)amino]-3-(3-fluorophenyl)propanoate (S)-2-TERT-BUTOXYCARBONYLAMINO-3-(3-FLUORO-PHENYL)-PROPIONIC ACID
CAS	114873-01-7
InChI	InChI=1/C14H18FNO4/c1-14(2,3)20-13(19)16-11(12(17)18)8-9-5-4-6-10(15)7-9/h4-7,11H,8H2,1-3H3,(H,16,19)(H,17,18)/t11-/m1/s1
InChIKey	FPCCREICRYPTTL-NSHDSACASA-N

Boc-3-Fluoro-L-phenylalanine - Physico-chemical Properties

Molecular Formula	C14H18FNO4
Molar Mass	283.3
Density	1.1918 (estimate)
Melting Point	75-80°C
Boling Point	425.0±40.0 °C(Predicted)
Flash Point	210.8°C
Vapor Presure	5.57E-08mmHg at 25°C
Appearance	Light brown powder
BRN	5347375
pKa	3.82±0.10(Predicted)
Storage Condition	Sealed in dry,Room Temperature
Refractive Index	1.517
MDL	MFCD00672522
Physical and Chemical Properties	Storage Conditions: Keep Cold WGK Germany:3

Boc-3-Fluoro-L-phenylalanine - Risk and Safety

Hazard Symbols	Xi - Irritant
Safety Description	24/25 - Avoid contact with skin and eyes.
WGK Germany	3
Hazard Note	Irritant/Keep Cold
Hazard Class	IRRITANT

Boc-3-Fluoro-L-phenylalanine - Introduction

BOC-L-3-Fluorophenylalanine is an organic compound with the chemical formula [C6H5CH2CH(NHBoc)COOH]. The following is a description of the properties, uses, preparation and safety information of BOC-L-3-fluorophenylalanine:

1. properties: BOC-L-3-fluorophenylalanine is a white crystalline solid, stable at room temperature. It has strong acidity and certain water solubility. It can be hydrolyzed under acidic conditions. An important feature of this compound is the introduction of a fluoro group, which increases its selectivity for specific enzymes in the organism.

2. Purpose: BOC-L-3-fluorophenylalanine is an important amino acid protecting group. It can be used as a protecting group in organic synthesis to control the reactivity of specific regions. In addition, BOC-L-3-fluorophenylalanine can also be used in the synthesis of polypeptides and proteins, as a reaction substrate or intermediate.

3. Preparation Method: The preparation of BOC-L-3-fluorophenylalanine usually starts from L-3-fluorophenylalanine. First, L-3-fluorophenylalanine is reacted with a BOC protecting agent to produce BOC-L-3-fluorophenylalanine.

4. Safety Information: BOC-L-3-Fluorophenylalanine is stable under general operating conditions, but is susceptible to hydrolysis under acidic conditions. Use should avoid contact with skin and eyes, should wear the appropriate protective equipment. In addition, it should be stored in a dry, ventilated place away from fire. For specific safe handling of BOC-L-3-FPHALANINE, reference should also be made to the safety data sheet of the product and the relevant safe handling procedures.

Last Update：2024-04-10 22:29:15