Boc-Ala-OSu
boc-L-alanine hydroxysuccinimide ester
CAS: 3392-05-0
Molecular Formula: C12H18N2O6
Boc-Ala-OSu - Names and Identifiers
| Name | boc-L-alanine hydroxysuccinimide ester |
| Synonyms | Boc-Ala-Osu Boc-Ala-OSu BOC-L-ALA-OSU BOC-D-ALA-OSU BOC-D-ALANINE-OSU boc-L-alanine hydroxysuccinimide ester BOC-D-ALANINE-HYDROXYSUCCINIMIDE ESTER Boc-L-Alanine N-hydroxysuccinimde ester BOC-D-ALANINE N-HYDROXYSUCCINIMIDE ESTER N-ALPHA-T-BOC-D-ALANINE N-HYDROXYSUCCINIMIDE ESTER succinimido (S)-2-[(tert-butoxycarbonyl)amino]propionate Succinimido (S)-2-[(tert-butoxycarbonyl)amino]propionate 2,5-dioxopyrrolidin-1-yl N-(tert-butoxycarbonyl)alaninate |
| CAS | 3392-05-0 |
| EINECS | 222-229-7 |
| InChI | InChI=1/C12H18N2O6/c1-7(13-11(18)19-12(2,3)4)10(17)20-14-8(15)5-6-9(14)16/h7H,5-6H2,1-4H3,(H,13,18) |
Boc-Ala-OSu - Physico-chemical Properties
| Molecular Formula | C12H18N2O6 |
| Molar Mass | 286.28 |
| Density | 1.27±0.1 g/cm3(Predicted) |
| Melting Point | 161-163°C |
| Specific Rotation(α) | -52 º (c=2.5% in dioxane) |
| BRN | 3560476 |
| pKa | 10.81±0.46(Predicted) |
| Storage Condition | -20°C |
| Sensitive | Moisture Sensitive |
| Refractive Index | 1.51 |
Boc-Ala-OSu - Risk and Safety
| Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. |
| WGK Germany | 3 |
| FLUKA BRAND F CODES | 3-10-21 |
| HS Code | 29224999 |
Boc-Ala-OSu - Introduction
boc-L-alanine hydroxysuccinimide (boc-L-alanine hydroxysuccinimide ester) is an organic compound with the following properties:
1. appearance: usually white crystal or crystalline powder.
2. molecular formula: C14H20N2O6.
3. Molecular weight: 312.32g/mol.
4. solubility: soluble in organic solvents, such as methanol, ethanol and dichloromethane.
boc-L-alanine hydroxysuccinimide ester is commonly used in chemical research on peptide synthesis and modification. Its main uses are as follows:
1. Peptide synthesis: As a peptide synthesis reagent, it is used to introduce Boc protecting group and succinimide ester group in chemical synthesis. It can react with the C- terminus of an amino acid or peptide chain to construct more complex peptide sequences.
2. Medical research: It can be used to develop new drug molecules or functional modification in drug delivery systems.
The common method for preparing boc-L-alanine hydroxysuccinimide ester is to react Boc-alanine with succinimide ester. The reaction is usually carried out at room temperature or with heating at room temperature, and a base is used as a catalyst during the reaction.
For safety information, boc-L-alanine hydroxysuccinimide ester is a chemical agent and should be handled with caution. Here are some general safety recommendations:
1. contact: try to avoid contact with skin, eyes and respiratory tract. If irritation occurs after contact, rinse immediately with plenty of water.
2. inhalation: should be operated in a well ventilated place to avoid inhalation of dust or vapor. If inhaled overdose, immediately go to a well-ventilated place and seek medical help.
3. storage: boc-L-alanine hydroxysuccinimide ester should be stored in a dry, dark and well-ventilated place, away from fire and flammable materials.
However, please note that any operation using chemical reagents should follow laboratory safety procedures and take appropriate measures according to the specific situation.
1. appearance: usually white crystal or crystalline powder.
2. molecular formula: C14H20N2O6.
3. Molecular weight: 312.32g/mol.
4. solubility: soluble in organic solvents, such as methanol, ethanol and dichloromethane.
boc-L-alanine hydroxysuccinimide ester is commonly used in chemical research on peptide synthesis and modification. Its main uses are as follows:
1. Peptide synthesis: As a peptide synthesis reagent, it is used to introduce Boc protecting group and succinimide ester group in chemical synthesis. It can react with the C- terminus of an amino acid or peptide chain to construct more complex peptide sequences.
2. Medical research: It can be used to develop new drug molecules or functional modification in drug delivery systems.
The common method for preparing boc-L-alanine hydroxysuccinimide ester is to react Boc-alanine with succinimide ester. The reaction is usually carried out at room temperature or with heating at room temperature, and a base is used as a catalyst during the reaction.
For safety information, boc-L-alanine hydroxysuccinimide ester is a chemical agent and should be handled with caution. Here are some general safety recommendations:
1. contact: try to avoid contact with skin, eyes and respiratory tract. If irritation occurs after contact, rinse immediately with plenty of water.
2. inhalation: should be operated in a well ventilated place to avoid inhalation of dust or vapor. If inhaled overdose, immediately go to a well-ventilated place and seek medical help.
3. storage: boc-L-alanine hydroxysuccinimide ester should be stored in a dry, dark and well-ventilated place, away from fire and flammable materials.
However, please note that any operation using chemical reagents should follow laboratory safety procedures and take appropriate measures according to the specific situation.
Last Update：2024-04-09 20:02:46
